Evidence map›Paper›PMID 41018225›Full record

ArticleFrontiers in aging2025

Chromogranin a gene variants influence survival at old age through pleiotropic effects on multiple age-related traits.

Paolina Crocco, Rossella La Grotta, Francesco De Rango, Giuseppe Passarino, Serena Dato, Giuseppina Rose

Abstract read
In one paragraph

Article in Frontiers in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paolina CroccoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.
Rossella La GrottaDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.
Francesco De RangoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.
Giuseppe PassarinoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.
Serena DatoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.
Giuseppina RoseDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging, age-related diseases, and longevity are interconnected processes influenced by shared molecular and genetic mechanisms. In this study, we investigated the role of genetic variation in the Chromogranin A (

Indexed as

age-related diseasesagingChromogranin AcvdlongevityMMSESNPTyG index

Identifiers

PMID41018225
PMCPMC12463820

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.