Evidence map›Paper›PMID 41017921›Full record

ArticleFood chemistry: X2025

Quantification of acrylamide in infant formula

Jiahui Ma, Xiaomin Li, Shuangxia Luo, Xianjiang Li, Qinghe Zhang, Xiong Yin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiahui MaFood Safety Analysis Laboratory, Division of Chemical Metrology and Analytical Science, Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, National Institute of Metrology China, Beijing 100029, PR China.
Xiaomin LiFood Safety Analysis Laboratory, Division of Chemical Metrology and Analytical Science, Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, National Institute of Metrology China, Beijing 100029, PR China.
Shuangxia LuoFood Safety Analysis Laboratory, Division of Chemical Metrology and Analytical Science, Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, National Institute of Metrology China, Beijing 100029, PR China.
Xianjiang LiFood Safety Analysis Laboratory, Division of Chemical Metrology and Analytical Science, Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, National Institute of Metrology China, Beijing 100029, PR China.
Qinghe ZhangFood Safety Analysis Laboratory, Division of Chemical Metrology and Analytical Science, Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, National Institute of Metrology China, Beijing 100029, PR China.
Xiong YinCollege of Chemistry, State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accurate quantification of acrylamide within complex infant formulas remain a significant challenge. This study validates a novel method for analyzing acrylamide in infant formula, which combines the quick, easy, cheap, effective, rugged, safe (QuEChERS) pretreatment approach with the isotope dilution HPLC-MS/MS technique. The optimized QuEChERS procedure effectively eliminates co-extracted matrix interferences and achieves high extraction efficiency. Notably, this approach simultaneously accomplishes a recovery rate of 103 % to 105 %, a relative standard deviation of less than 1.6 %, and a limit of quantification at 0.90 μg/kg. The high accuracy of this proposed method is further confirmed using commercially certified reference material (CRM,

Indexed as

2-propenamideInfant formulaIsotope dilution liquid chromatography- tandem mass spectrometryMatrix interferenceQuEChERS

Identifiers

PMID41017921
PMCPMC12466240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.