Evidence map›Paper›PMID 41017893›Full record

ArticleIndian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

Survival Rates and Predictors of Mortality in Lung Cancer: A Multi-Centre Study in Kerala.

Nisha Jose, Manuprasad Avaronnan, Narayanankutty Warrier, Anoop Velayudan

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Article in Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Nisha JoseDepartment of Community Medicine, Achutha Menon Centre for Health Sciences Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Manuprasad AvaronnanDepartment of Clinical Haematology and Medical Oncology, Malabar Cancer Centre, Thalassery, Kerala, India.
Narayanankutty WarrierDepartment of Medical Oncology, MVR Cancer Centre, Poolacode, Kerala, India.
Anoop VelayudanECD Division, Indian Council of Medical Research, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung cancer is a major health problem in India and accounts for 5.9% of all cancers and 8.1% of all cancer-related deaths. Survival analysis studies are scarce in India as they require long-term follow-up and a good database. Therefore, the present study was conducted to understand survival rates and factors associated with lung cancer mortality in India. Methods: It was a hospital-based registry, wherein six hospitals were selected from three zones - north, central, and south zones of Kerala. Patients of pathologically proven primary lung cancer (ICD-11 code C 33 and C 36) were recruited. All patients were followed up for 2 years from the date of diagnosis. Results: A total of 761 patients were registered from six tertiary care hospitals of Kerala who were diagnosed with primary lung cancer during the period 2017-2019. The median survival of the study population was 8.6 months (IQR 2.9-21.6). The cumulative mortality rates at the end of 6 months, 1 year, and 2 years were 39.9%, 57.8%, and 70.2%, respectively. The overall mortality rate was 6.38 (CI 3.03-12.97) per 100 person months. In adjusted Cox-proportional hazard model, participants with lymph node status of N2 (HR = 4.9, 95% CI 1.0-23.6), N3 (HR = 5.9, 95% CI 0.53-66.7), and NX (HR = 31.7, 95% CI 2.8-354.7) had higher mortality risk compared to those with N1 status. Conclusion: This study includes significant implications for policy in cancer diagnosis and first health system contact for treatment. Findings are crucial to effectively stratify risk in lung cancer beyond smoking history, comprehensive identification, and assessment of potential predictors of mortality.

Indexed as

Keralalung cancermortalitysurvival ratestertiary hospital

Identifiers

PMID41017893
PMCPMC12470342

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