Evidence map›Paper›PMID 41017861›Full record

ArticleHealth science reports2025

Predicting the Determinants of Colorectal Cancer Screening Behaviors Using Protection Motivation Theory: A Cross-Sectional Partial Least Squares Structural Equation Modeling Analysis.

Mahdi Gholian-Aval, Bahareh Behrouzi, Jamshid Jamali

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Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mahdi Gholian-AvalSocial Determinants of Health Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-6182-4965
Bahareh BehrouziStudent Research Committee Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0003-0503-5790
Jamshid JamaliSocial Determinants of Health Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-9681-8231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) screening reduces mortality by 40%-60%, yet participation remains low globally. In this study, we applied protection motivation theory (PMT) to identify determinants of CRC screening behavior in Iran using partial least squares structural equation modeling (PLS-SEM). Design and Methods: This cross-sectional study was conducted on 433 adults over 50 years of age using stratified sampling in Neyshabur, Iran in 2024. Participants completed a validated 43-item PMT questionnaire assessing key cognitive factors (perceived sensitivity, severity, self-efficacy, response efficacy, response costs, fear, rewards, and behavioral intention), with self-reported screening behavior as the outcome. Results: Among the PMT constructs, self-efficacy had the highest mean score (69.43 ± 18.97 out of 100), while actual screening behavior had the lowest (26.12 ± 9.93 out of 100). PLS-SEM analysis revealed significant pathways: perceived severity ( Conclusion: Participants demonstrated moderate intention (54.8 of 100) yet low screening behavior (26.1 of 100), highlighting a critical intention-behavior gap. While PMT constructs effectively predicted screening intention, their limited ability to explain behavior underscores the influence of contextual barriers beyond cognitive appraisals in this Iranian cohort. Future interventions should integrate PMT-based education targeting threat appraisal with system-level strategies (e.g., mailed test kits, navigational support) to bridge this implementation gap.

Indexed as

colorectal cancerIranpartial least squaresprotection motivation theoryscreeningstructural equation modeling

Identifiers

PMID41017861
PMCPMC12464729

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.