ArticleJournal of veterinary internal medicine
A Prospective Multicenter Observational Study Assessing Incidence and Risk Factors for Acute Transfusion Reactions in Cats.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A Prospective Multicenter Observational Study Assessing Incidence and Risk Factors for Acute Transfusion Reactions in Cats.Journal of veterinary internal medicineArticle
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe reported incidence of blood product transfusion reaction (TR) in cats varies greatly.
objectiveEvaluate the incidence and practices surrounding acute TRs in cats receiving feline blood products, using Transfusion Reaction Small Animal Consensus Statement (TRACS) definitions. ANIMALS: Cats (n = 444) that received feline blood products (n = 608) between March 2022 and January 2024.
methodsProspective, multicenter observational study at referral hospitals (n = 14) in the United States, United Kingdom, and Australia documenting the incidence of acute TRs in cats receiving allogenic blood transfusions.
resultsAcute TR incidence was 7.8% (95% confidence interval [CI], 5.6-10.6) for red blood cell (RBC)-containing products and 1.1% (95% CI, 0.0-5.9) for plasma products. Febrile nonhemolytic transfusion reactions (FNHTRs) were the most common in RBC-containing products (incidence, 5.7%; 95% CI, 3.8-8.1). Age of RBC unit (adjusted odds ratio [aOR], 1.04 per day; 95% CI, 1.00-1.07) and administering a RBC unit with an infusion pump rather than a syringe driver (aOR, 4.7; 95% CI, 1.43-15.54) were associated with an increased odds of FNHTR. Of transfusions discontinued (n = 28) because of a potential TR, 46.4% did not fulfill TRACS criteria for any TR. Death occurred within 24 h of a transfusion event in 18.3% but was not associated with the development of a TR (odds ratio [OR], 0.76; 95% CI, 0.29-1.99). CONCLUSIONS AND CLINICAL IMPORTANCE: Transfusion reaction incidence in cats, as defined using TRACS guidelines, is reported. Febrile nonhemolytic TRs were the most common and were associated with increasing RBC unit age and administering RBC via an infusion pump.
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