Evidence map›Paper›PMID 41016935›Full record

ArticleEye (London, England)2025

Evaluation of optic nerve head morphology of small optic discs in healthy eyes with different optical coherence tomography parameters.

Kubra Caglar, Gulsah Gumus Akgun, Cigdem Altan, Nese Alagoz, Ihsan Cakir, Tekin Yasar

Abstract readComparative Study
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kubra CaglarUniversity of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey. kubraa1629@gmail.com.ORCID http://orcid.org/0009-0006-3790-7687
Gulsah Gumus AkgunUniversity of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-1954-2400
Cigdem AltanUniversity of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-0908-6619
Nese AlagozUniversity of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-0372-8967
Ihsan CakirUniversity of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-3784-1607
Tekin YasarUniversity of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTo compare Bruch's Membrane Opening- Minimum Rim Width (BMO-MRW), peripapillary retinal nerve fibre layer (pRNFL) thickness at different peripapillary diameters, and ganglion cell layer- inner plexiform layer (GCL-IPL) thickness between in eyes with small optic discs and normal discs.

methodIn this cross-sectional study, we selected healthy eyes. The patients were divided into two groups: the first group consisted of those with a disc area smaller than 1.60 mm² (Small disc group, 92 patients), and the second group included those with a disc area between 1.60 mm² and 2.50 mm² (Normal disc group, 71 patients). Spectralis OCT (Heidelberg Engineering, Inc., Heidelberg, Germany) was used to measure BMO-MRW and pRNFL thickness at three different diameters (3.5 mm, 4.1 mm, and 4.7 mm) using the Glaucoma Module Premium Edition (GMPE) software version 6.0. The thickness of GCL-IPL and pRNFL at a diameter of 3.4 mm were measured using Cirrus OCT (Carl Zeiss Meditec, Dublin, CA, USA).

resultsIn the small disc group, the disc area, rim area, and cup/disc ratio were smaller compared to the normal disc group (p < 0.05 for each). In the small disc and normal disc groups, pRNFL thickness at each three diameters (3.5 mm, 4.1 mm, and 4.7 mm) measured by Spectralis OCT were similar in all quadrants (superior temporal, superior nasal, nasal, inferonasal, inferotemporal, and temporal) and GCL-IPL (average, minimum) and pRNFL thickness measured with Cirrus OCT were similar in all quadrants (superior, nasal, inferior, and temporal). However, BMO-MRW measurements in all quadrants were larger in the small disc group (p < 0.05 for all).

conclusionRNFL and GCL-IPL measurements were similar in all quadrants in both group. However, BMO-MRW measurements were higher in all quadrants in the small disc groups.

Indexed as

Optic DiskRetinal Ganglion CellsTomography, Optical CoherenceAdultAgedBruch MembraneCross-Sectional StudiesFemaleHealthy VolunteersHumansIntraocular PressureMaleMiddle AgedNerve FibersVisual Fields

Identifiers

PMID41016935
PMCPMC12623445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.