Evidence map›Paper›PMID 41015589›Full record

ArticleJournal of human hypertension2025

Impact of adherence and study design on CPAP effectiveness in resistant hypertension.

Abdullah Sarıhan, Macit Kalçık, Mucahit Yetim

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Journal of human hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abdullah SarıhanDepartment of Cardiology, Facult of Medicine, Hitit University, Corum, Turkey.ORCID http://orcid.org/0009-0001-8505-9460
Macit KalçıkDepartment of Cardiology, Facult of Medicine, Hitit University, Corum, Turkey. macitkalcik@yahoo.com.ORCID http://orcid.org/0000-0002-8791-4475
Mucahit YetimDepartment of Cardiology, Facult of Medicine, Hitit University, Corum, Turkey.ORCID http://orcid.org/0000-0002-2444-7523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This letter comments on the recent article by Fernandes et al. evaluating the long-term effects of continuous positive airway pressure (CPAP) in patients with resistant hypertension and obstructive sleep apnea. While the study provides valuable insights into prolonged CPAP use, its non-randomized design and reliance on per-protocol analyses limit the generalizability of the findings. Evidence from previous randomized and multicenter studies suggests that the benefits of CPAP are modest and often diminish over time. Moreover, the exclusive focus on blood pressure outcomes overlooks broader cardiovascular effects, and the role of psychosocial and socioeconomic determinants of adherence remains underexplored. Future large-scale, randomized studies that integrate clinical and behavioral factors are needed to better define the long-term role of CPAP in resistant hypertension management.

Indexed as

Continuous Positive Airway PressureHypertensionPatient ComplianceResearch DesignSleep Apnea, ObstructiveAntihypertensive AgentsBlood PressureHumansTreatment OutcomeAntihypertensive Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.