Evidence map›Paper›PMID 41015555›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2025

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Jiayi Yang, Yang Luo, Zixuan Zhu, Wenbin Tang

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Mechanisms of pyroptosis in metabolic diseases].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiayi YangDepartment of Hospital Infection Control Center, Xiangya Hospital, Central South University, Changsha 410008. jiayi2355@csu.edu.cn.
Yang LuoDepartment of General Practice, Xiangya Hospital, Central South University, Changsha 410008.
Zixuan ZhuDepartment of General Practice, Xiangya Hospital, Central South University, Changsha 410008.
Wenbin TangNational Clinical Research Center for Geriatric Diseases, Xiangya Hospital, Changsha 410008. tangwenbin@csu.edu.cn.

Funding

This work was supported by the Natural Science Foundation of Hunan Province, China 2021JJ70149
6 · The paper itself

Abstract

objectivesPyroptosis plays a critical role in tubulointerstitial lesions of diabetic kidney disease (DKD). Annexin A2 (ANXA2) is involved in cell proliferation, apoptosis, and adhesion and may be closely related to DKD, but its specific mechanism remains unclear. This study aims to investigate the role and molecular mechanism of

methodsHuman renal tubular epithelial HK-2 cells were divided into a normal glucose group (5.5 mmol/L), a high glucose group (30.0 mmol/L), and a osmotic control group (24.5 mmol/L mannitol+5.5 mmol/L glucose).

resultsHigh glucose upregulated

conclusions

Indexed as

Annexin A2Epithelial CellsGlucoseKidney TubulesNF-kappa BPyroptosisCell LineCell ProliferationDiabetic NephropathiesFeedback, PhysiologicalHumansTranscription Factor RelAAnnexin A2ANXA2 protein, humanGlucoseNF-kappa BTranscription Factor RelAAnnexin A2diabetic kidney diseaseNLRP3nuclear factor κBpositive feedback looppyroptosis

Identifiers

PMID41015555
PMCPMC12464933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.