ArticleAmerican journal of physiology. Lung cellular and molecular physiology2025
Computer model-based injury prediction and evaluation of lung function in mice with acute and ventilator-induced lung injuries.
Article in American journal of physiology. Lung cellular and molecular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Invasive mechanical ventilation is a lifesaving intervention for patients with acute respiratory distress syndrome (ARDS) but it also causes ventilator-induced lung injury (VILI) that can be challenging to avoid due to interpatient and temporal heterogeneity. Thus, the aim of this study was to characterize and predict experimental VILI using readily available measures of lung function. Initially healthy (CTL) and hydrochloric acid (HCL) lung-injured mice were ventilated for 4 h at positive end-expiratory pressure (PEEP) 1, 3, or 8 cmH
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