Evidence map›Paper›PMID 41015405›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2025

Conventional tobacco and electronic cigarettes differentially affect cardiovascular health in male and female mice.

Candice J Lao, Maria C Jordan, Juan Carlos Rivera, Yin Tintut, Karla Luna, William Ramirez-Trillo, Trent Yamamoto, Bilal Pandit, Cherie Huang, Angela Li and 8 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Candice J LaoDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.ORCID 0000-0001-7158-6289
Maria C JordanDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Juan Carlos RiveraDepartment of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States.ORCID 0000-0002-0927-218X
Yin TintutDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.ORCID 0000-0003-0156-2307
Karla LunaDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.ORCID 0009-0000-3348-1646
William Ramirez-TrilloDepartment of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States.
Trent YamamotoDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Bilal PanditDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Cherie HuangDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Angela LiDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Sophia Lewis WangDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Thalia NguyenDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Valentina CastroDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Ayushi KothariDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Victoria C ChenDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Xuesi M ShaoDepartment of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States.ORCID 0000-0002-5165-347X
Theodore C FriedmanDepartment of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States.ORCID 0000-0001-9555-7626
Kenneth P RoosDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.ORCID 0000-0002-2823-5069

Funding

Role of intermittent activation of parathyroid hormone receptor in exercise-induced vascular calcificationR01HL151391 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEMER, LINDA L., TINTUT, YIN · 2021 to 2024
$2.2M
Regulation of PTH-induced Osteoanabolism by Inflammatory LipidsR01DK081346 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TINTUT, YIN · 2009 to 2013
$1.8M
Serotonin receptor contribution to inflammation-induced calcific aortic valve diseaseR01HL137647 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEMER, LINDA L., TINTUT, YIN · 2019 to 2022
$1.6M
Role of Inhibitory SMADs in Calcific Aortic Valve DiseaseR01HL114709 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEMER, LINDA L., TINTUT, YIN · 2012 to 2015
$1.5M
DOD | MHS | Congressionally Directed Medical Research Programs (CDMRP) PR-190942DOD | MHS | Congressionally Directed Medical Research Programs (CDMRP) PR-190942-P1HHS | NIH | NHLBI | Division of Intramural Research (DIR) HL-137647HHS | NIH | NHLBI | Division of Intramural Research (DIR) HL-151391NHLBI NIH HHS R01 HL114709NHLBI NIH HHS R01 HL137647NHLBI NIH HHS R01 HL151391NIDDK NIH HHS R01 DK081346
6 · The paper itself

Abstract

Although promoted as a safer alternative, the cardiovascular effects of electronic cigarettes (E-cigs) compared with tobacco cigarettes (T-cigs) are largely unknown. Thus, we evaluated aerosol exposures and the potential additive effects of a Western diet (WD) on cardiovascular health in multiple cohorts of hyperlipidemic (

Indexed as

AtherosclerosisDiet, WesternElectronic Nicotine Delivery SystemsHyperlipidemiasNicotineNicotinic AgonistsTobacco ProductsVapingAerosolsAnimalsDisease Models, AnimalE-Cigarette VaporEnergy IntakeFemaleMaleMiceAerosolsE-Cigarette VaporNicotineNicotinic Agonistsatherosclerosiselectronic cigarettessex differencestobacco cigarettesventricular dysfunction

Identifiers

PMID41015405
PMCPMC13021282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.