ReviewCell biochemistry and biophysics2026
Strategic Targeting of Mitochondria: Bridging Biology and Therapy for Health Benefits.
Review in Cell biochemistry and biophysics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondria perform many crucial cellular functions, including energy production and calcium balance, while controlling pathways determining cell survival and death. The capability of mitochondria to respond dynamically to cellular stimuli plays a crucial role in keeping cells and tissues balanced. Mitochondrial quality control impairment during disease causes dysfunctional mitochondria to accumulate, which drives disease progression. The alterations demonstrate how mitochondria play a crucial role in health and disease, positioning them as valuable targets for therapeutic interventions. Investigators can develop precision-targeted therapies to exploit mitochondrial features, including their double-membrane structure, independent genome, and unique electrochemical properties. Mitochondrial-targeted approaches offer dual benefits, such as therapeutic strategies that restore mitochondrial function in degenerative diseases while inducing cell death through mitochondrial mechanisms in cancer conditions have been developed. A variety of methods have been created to utilize mitochondrial properties for drug delivery, but their therapeutic capabilities are not fully understood. The current review delivers a detailed examination of mitochondrial applications in disease treatment and reveals new mitochondrial properties with substantial potential for therapeutic development. This review seeks to fill current knowledge gaps and create opportunities for novel mitochondria-targeted treatment approaches by examining existing methods and prospects.
Indexed as
Identifiers
41014452What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.