ArticleJournal of veterinary internal medicine
Risk Factors for Pituitary Macrotumor in Dogs With Hypercortisolism.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Risk Factors for Pituitary Macrotumor in Dogs With Hypercortisolism.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiagnosing pituitary macrotumor in dogs with hypercortisolism requires advanced imaging, which is not feasible for every case. Identifying risk factors that can guide the decision to pursue imaging would be valuable.
objectiveDetermine clinical and physical examination findings that are associated with an increased likelihood of pituitary macrotumors in dogs with hypercortisolism. ANIMALS: A total of 130 dogs diagnosed with hypercortisolism.
methodsRetrospective study to analyze medical records for data on age, sex, breed, clinical signs, physical findings, endocrine test results, imaging results, diagnosis, and treatment. Logistic regression was used to identify risk factors for pituitary macrotumor, defined by a pituitary height/brain area ratio ≥ 0.4.
resultsRisk factors for pituitary macrotumor included diagnosis of hypercortisolism at ≤ 10.9 years of age (odds ratio [OR], 0.718; p < 0.05), French Bulldog breed (OR, 21.0; p < 0.01), and presence of neurologic signs (OR, 10.9; p < 0.001). CONCLUSION AND CLINICAL IMPORTANCE: Advanced pituitary imaging should be recommended in dogs with hypercortisolism ≤ 10.9 years of age, French Bulldogs, and those presenting with neurological signs because these factors significantly increase the likelihood of pituitary macrotumor in dogs with hypercortisolism.
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