Evidence map›Paper›PMID 41014052›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

The association of mild cognitive impairment with outpatient visits for hypertension.

Mellanie V Springer, Yi Chen, Slim Benloucif, Francine Grodstein, Bryan D James, Ana W Capuano, Mousumi Banerjee, Julie P W Bynum

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The association of mild cognitive impairment with outpatient visits for hypertension.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mellanie V SpringerDepartment of Neurology and Stroke Program, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-6281-0143
Yi ChenRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Slim BenloucifDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Francine GrodsteinRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Bryan D JamesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Ana W CapuanoRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Mousumi BanerjeeInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.
Julie P W BynumInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Rush Alzheimer's Disease Research CenterP30AG072975 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Julie A. Schneider · 2021 to 2026
$24.7M
RISK FACTORS, PATHOLOGY, AND CLINICAL EXPRESSIONS OF ADR01AG015819 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1998 to 2024
$21.4M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Use of Healthcare Across the Full Continuum of Cognitive Health and Decline in Older AdultsR01AG079226 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Julie PW Bynum, FRANCINE GRODSTEIN · 2022 to 2026
$3.1M
Predictors and consequences of the timing and accuracy of clinical dementia diagnosisR01AG072559 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Bryan David James · 2022 to 2026
$2.9M
Partnering with an Urban Safety Net Hospital to Deliver Stroke Preparedness in the Emergency DepartmentK01NS117555 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SPRINGER, MELLANIE V · 2020 to 2024
$1.2M
NIA NIH HHS P30 AG072975NIA NIH HHS R01 AG015819NIA NIH HHS R01AG015819NIA NIH HHS R01 AG017917NIA NIH HHS R01AG017917NIA NIH HHS R01 AG022018NIA NIH HHS R01AG022018NIA NIH HHS R01 AG072559NIA NIH HHS R01AG072559NIA NIH HHS R01 AG079226NIA NIH HHS R01AG079226NINDS NIH HHS K01 NS117555NINDS NIH HHS K01NS117555Rush Alzheimer's Disease Research Center P30AG072975
6 · The paper itself

Abstract

introductionHypertension management is critically important to reduce the risk of conversion of mild cognitive impairment (MCI) to dementia. The degree to which older adults with hypertension and MCI engage in outpatient ambulatory care for hypertension management is unclear.

methodsAmong older adults with hypertension in the Rush Alzheimer's Disease Center (RADC) cohorts (2011 to 2019), we used repeated measures negative binomial regression to evaluate the association between cognitive status (MCI vs no cognitive impairment [NCI]) and number of annual outpatient clinic visits for hypertension evaluation and management (E&M) (primary outcome).

resultsMCI (n = 1013 person-years) was associated with 8% fewer outpatient visits for hypertension versus older adults with NCI (n = 4373 person-years) (relative incidence ratio [RIR] 0.92, p < 0.01). DISCUSSION: Despite the known adverse cognitive effects of hypertension, older adults with MCI may be less likely to engage in outpatient hypertension management. HIGHLIGHTS: Fewer outpatient hypertension visits among adults with MCI versus NCI. Fewer primary care hypertension visits among adults with MCI versus without MCI. Need for interventions to engage adults with hypertension and MCI in outpatient care.

Indexed as

Ambulatory CareCognitive DysfunctionHypertensionOutpatientsAgedAged, 80 and overCohort StudiesFemaleHumansMaleambulatory carehypertensionmild cognitive impairmentoutpatient care utilization

Identifiers

PMID41014052
PMCPMC12475831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.