Evidence map›Paper›PMID 41013757›Full record

ArticleBiology of sex differences2025

Genetic variants (Lhcgr

Xie Qigen, Xia Kai, Cao Haiming, Xu Zhe, Gao Yong, Deng Chunhua

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology of sex differences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xie Qigen *Department of Pediatric Surgery, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan Road 2, Guangzhou, 510080, China.
Xia Kai *Department of Andrology, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan Road 2, Guangzhou, 510080, China.
Cao Haiming *Department of Andrology, Reproductive Center of the Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518000, China.
Xu ZheDepartment of Pediatric Surgery, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan Road 2, Guangzhou, 510080, China. xzhe@mail.sysu.edu.cn.
Gao YongReproductive Medicine Center, The Key Laboratory for Reproductive Medicine of Guangdong Province, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, Guangdong, China. gyong@mail.sysu.edu.cn.
Deng ChunhuaDepartment of Andrology, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan Road 2, Guangzhou, 510080, China. dengchh@mail.sysu.edu.cn.

Funding

Medical Research Funding of Guangdong A2022499National Natural Science Foundation of China 81971314
6 · The paper itself

Abstract

backgroundEmerging evidence suggests that genetic variants and environmental toxicants may synergistically contribute to DSD. To test this hypothesis, we employed Lhcgr

methodsPregnant wild-type (WT) dams (mated with Lhcgr

resultsLhcgr

conclusionsThis study verifies that Genetic variants (Lhcgr

Indexed as

Diethylhexyl PhthalateDisorders of Sex DevelopmentPrenatal Exposure Delayed EffectsReceptors, LHAnimalsFemaleGene-Environment InteractionGenetic VariationMaleMiceMice, Inbred C57BLPregnancyTestosteroneDiethylhexyl PhthalateReceptors, LHTestosteroneDEHPDisorders/differences of sex developmentLHCGRSynergistic effect

Identifiers

PMID41013757
PMCPMC12465185

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.