ArticleBMC oral health2025
Nanoparticle functionalization and sonic activation in photodynamic therapy: effects on push-out bond strength of endodontic sealers.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study evaluated the effects of sonic activation and graphene-functionalized methylene blue on the push-out bond strength of two endodontic sealers, AH Plus and Bio C, following Photodynamic therapy (PDT).
methodsSixty extracted single-rooted human teeth were divided into six groups (n = 10), treated with either 5% NaOCl (Groups 1 & 2), MB-based PDT (Groups 3 & 4), or MB-rGO-based PDT (Groups 5 & 6). In Groups 2, 4, and 6, sonic activation was applied prior to laser irradiation. Each group was further divided based on the sealer used: AH Plus or Bio-C. One mm-thick root slices from the coronal and middle thirds were subjected to push-out bond strength testing. Statistical analysis included one-way ANOVA, Tukey's post-hoc, and independent t-tests.
resultsGroup 6 (MB-rGO + Sonic Activation + PDT) showed the highest bond strength for both AH Plus (6.07 ± 0.99 MPa) and Bio-C (5.54 ± 0.76 MPa), while Group 3 (MB + PDT) showed the lowest. Significant differences were observed between groups for both sealers (p < 0.05). Sonic activation significantly enhanced bond strength in Bio-C Sealer (p = 0.026) but not in AH Plus (p = 0.124). AH Plus showed predominantly cohesive failures, whereas Bio-C exhibited more adhesive failures.
conclusionSonic activation and graphene functionalization significantly enhanced the bond strength of both sealers, with the highest values in the MB-rGO with activation group. AH Plus showed superior adhesion, attributed to its chemical interaction with dentin collagen, while Bio-C Sealer benefited from hydroxyapatite bonding and improved mechanical retention. These findings suggest that optimizing photodynamic therapy with nanotechnology and activation techniques can improve the adhesion and clinical performance of endodontic sealers.
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