Evidence map›Paper›PMID 41013548›Full record

ArticleJournal of orthopaedic surgery and research2025

Analysis of the anti-subsidence mechanical properties of novel 3D-printed titanium cages compared to conventional titanium cages.

Huiming Yang, Yuhang Wang, Junxian Miao, Jiangtao Wang, Hao Li, Yang Zhang, Liang Yan, Biao Wang

Abstract readComparative Study
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Huiming Yang *Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.ORCID http://orcid.org/0000-0003-4515-3695
Yuhang Wang *Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Junxian MiaoDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Jiangtao WangDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Hao LiDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Yang ZhangDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Liang YanDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China. yanliangdr5583@163.com.
Biao WangDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China. wangbiaowb1987@126.com.

Funding

General Cultivation Project of Xi'an Health Bureau 2024ms11Key Medical Research Project of Xi'an Science and Technology Bureau No.24YXYJ0006Key Research and Development Program of Shaanxi Province No.2020GXLH-Y-003Research Project of Xi'an Health Commission No. 2025yb14The National Key Research and Development Program of China No.2022YFC2407503
6 · The paper itself

Abstract

backgroundTitanium cage subsidence remains a common complication following anterior cervical corpectomy and fusion. 3D printing technology can optimize titanium cages, including high geometric matching and unique porous graded structures, providing a better option for improving titanium cage subsidence. This study aims to evaluate the mechanical properties of 3D-printed titanium cages and compare them with those of conventional titanium cages, providing preclinical data for future clinical trials.

methodsThe samples were divided into a 3D-printed titanium cage group and a conventional titanium cage group, with 5 samples in each group. A static compression test was conducted using the American Society for Testing and Materials (ASTM) F2077-14 standard to evaluate the stiffness of the titanium cages. A static subsidence test was conducted using the ASTM F2267-04 standard to evaluate the stiffness (K

resultsIn the static compression test, the stiffness of the 3D-printed titanium cage and the conventional titanium cage were (6562.60 ± 390.72) N/mm and (10252.40 ± 704.07) N/mm, respectively, with a statistically significant difference (P < 0.05). In the static subsidence test, the stiffness of the 3D-printed titanium cage system and the conventional titanium cage system were (258.60 ± 7.99) N/mm and (221.00 ± 20.36) N/mm, respectively, with a statistically significant difference (P < 0.05). Additionally, the stiffness (K

conclusionThe optimized 3D-printed titanium cage, featuring anatomical conformity and a 70% porous structure, demonstrates 19.5% improved anti-subsidence performance compared to conventional designs, addressing limitations in prior 3D-printed solutions, providing a promising and feasible solution for reducing the subsidence of titanium cages.

Indexed as

Materials TestingPrinting, Three-DimensionalSpinal FusionTitaniumHumansTitanium3D-printedAnterior cervical corpectomy and fusionCompression testSubsidenceSubsidence testTitanium cages

Identifiers

PMID41013548
PMCPMC12465666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.