Evidence map›Paper›PMID 41013536›Full record

ArticleGut pathogens2025

Global research landscape and advancements on the links between the gut microbiome and insulin resistance: hot issues, trends, future directions, and bibliometric analysis.

Sa'ed H Zyoud, Muna Shakhshir, Amani S Abushanab, Amer Koni, Moyad Shahwan, Ammar A Jairoun, Banan M Aiesh, Samah W Al-Jabi

Abstract read
In one paragraph

Article in Gut pathogens, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sa'ed H ZyoudDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, An-Najah National University, Nablus, 44839, Palestine. saedzyoud@yahoo.com.
Muna ShakhshirDepartment of Nutrition, An-Najah National University Hospital, Nablus, 44839, Palestine. muna.shakhshir@gmail.com.
Amani S AbushanabDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, An-Najah National University, Nablus, 44839, Palestine.
Amer KoniDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, An-Najah National University, Nablus, 44839, Palestine.
Moyad ShahwanDepartment of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates.
Ammar A JairounHealth and Safety Department, Dubai Municipality, Dubai, United Arab Emirates.
Banan M AieshInfection Control Department, An-Najah National University Hospital, Nablus, 44839, Palestine.
Samah W Al-JabiDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, An-Najah National University, Nablus, 44839, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is increasing evidence suggesting that the gut microbiota plays a key role in the development of insulin resistance (IR). Therefore, the present bibliometric study aimed to characterize the development trends and research hotspots of publications related to the gut microbiota and IR.

methodsPublications on the gut microbiota and IR between 2015 and 2024 were retrieved from the Scopus database. Bibliometric analyses were conducted with the VOSviewer version 1.6.20 software program.

resultsThe Scopus query (15 June 2025) retrieved 584 publications on the gut microbiota and IR. Most were research articles (n = 480, 82.19%), followed by reviews (n = 82, 14.04%). Output is highly skewed toward East Asia and North America, with China leading the list with 254 papers (43.49%), followed by the United States (96; 16.44%), Canada (44; 7.53%), and Germany (27; 4.62%). Term-cooccurrence mapping in VOSviewer (v1.6.20) of the 251 high-frequency keywords (≥ 15 occurrences) resolved three thematic clusters: Cluster 1 focused on the high-fat-diet gut-liver axis; Cluster 2 examined patient-centered epidemiology and clinical trials; and Cluster 3 investigated inflammatory and metabolic signalling.

conclusionsThe annual number of publications on the gut microbiota and IR has increased rapidly in the past ten years, demonstrating that the gut microbiota and IR have the potential to be researched precisely and are attracting increasing attention. The findings of this study can help researchers explore new directions for future research in this area and could serve as a reference for future academic research.

Indexed as

BibliometricGut microbiotaInsulin resistanceInsulin sensitivityMicrobiomeScopusVOSviewer

Identifiers

PMID41013536
PMCPMC12465385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.