Evidence map›Paper›PMID 41013533›Full record

ArticleBMC medical ethics2025

From chaos to symbiosis: exploring adaptive co-evolution strategies for generative AI and research integrity systems.

Wenqing Miao, Huan Zang, Qirui Liu, Tianlei Zheng, Yan Zhou, Chunmei Liu, Na Yang, Hengzhi Zhang, Yuwan Zhang, Ying Zhang and 3 more

Abstract read
In one paragraph

Article in BMC medical ethics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wenqing Miao *Department of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Huan Zang *Department of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Qirui Liu *Propaganda Department, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Tianlei ZhengSchool of Information and Control Engineering, China University of Mining and Technology, Xuzhou, Jiangsu, 221116, People's Republic of China.
Yan ZhouDepartment of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Chunmei LiuDepartment of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Na YangArtificial Intelligence Research Group, Medical Equipment Management Department, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Hengzhi ZhangDepartment of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Yuwan ZhangDepartment of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Ying ZhangDepartment of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China.
Shengli LiClinical Research Institute, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China. lishengli401@163.com.
Shenyang ZhangDepartment of Science and Technology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China. zhangshenyang0925@163.com.
Hao ZhangPresident's Office, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, People's Republic of China. zhanghao@xzhmu.edu.cn.

Funding

Project supported by the Affiliated Hospital of Xuzhou Medical University 2021G10Project supported by the Affiliated Hospital of Xuzhou Medical University 2024SK02the Soft Science Research Project of Xuzhou Policy Guidance Program KC23118
6 · The paper itself

Abstract

objectiveThe information age has transformed technologies across disciplines. Generative artificial intelligence (GenAI), as an emerging technology, has integrated into scientific research. Recent studies identify GenAI-related scientific research integrity concerns. Using Complex Adaptive Systems (CAS) theory, this research examines risk factors and preventive measures for each agent within the scientific research integrity management system during GenAI adoption, providing new perspectives for integrity management.

methodThis study applies CAS theory to analyze the scientific research integrity management system, identifying four core micro-level agents: researchers, research subjects, scientific research administrators, and academic publishing institutions. It examines macro-system complexity, agent adaptability, and the impact of agent interactions on the overall system. This framework enables analysis of GenAI's effects on the research integrity management system.

resultsThe scientific research integrity management system exhibits structural, hierarchical, and multidimensional complexities, with internal circulation of policy, funding, and information elements. In response to GenAI integration, four micro-level agents-researchers, research subjects, scientific research administrators, and academic publishing institutions-adapt their behaviors to systemic changes. Through these interactions, behavioral outcomes emerge at the macro level, driving evolution of the research integrity management system.

conclusionsRisks of scientific misconduct permeate the entire research process and require urgent governance. This study recommends that scientific research administrators promptly define applicable boundaries for GenAI in research to guide researchers. Concurrently, they should collaborate with relevant departments to establish regulatory frameworks addressing potential GenAI-related misconduct. Academic publishing institutions must assume quality assurance responsibilities by strengthening review and disclosure protocols. Furthermore, research integrity considerations should be systematically integrated into GenAI's technological development and refinement. HIGHLIGHTS: ● Develops an analytical framework grounded in Complex Adaptive Systems (CAS) theory to map evolving interactions among researchers, research subjects, scientific research administrators, and academic publishing institutions within GenAI-integrated research ecosystems.  ● Identifies self-reinforcing dynamics between GenAI adoption and integrity governance, wherein adaptive rule adjustments by agents reshape system-wide integrity thresholds.  ● Proposes adaptive governance mechanisms that balance innovation safeguards with integrity guardrails, emphasizing context-sensitive policy calibration over universal solutions.

Indexed as

Artificial IntelligenceBiomedical ResearchEthics, ResearchHumansResearch PersonnelGenerative artificial intelligenceResearch integrityScientific research management

Identifiers

PMID41013533
PMCPMC12465495

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.