Evidence map›Paper›PMID 41013529›Full record

ArticleJournal of orthopaedic surgery and research2025

Analysis of related factors affecting the postoperative clinical outcome of cervical ossification of the posterior longitudinal ligament.

Shuqing Chen, Changlin Lv, Xuanyu Dong, Ziang Zhang, Jianyi Li, Tianyu Bai, Xiaofan Du, Guodong Zhang, Jianwei Guo, Jiale Shao and 4 more

Abstract read
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Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Shuqing Chen *The affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Changlin Lv *The affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Xuanyu DongThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Ziang ZhangThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Jianyi LiThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Tianyu BaiThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Xiaofan DuThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Guodong ZhangThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Jianwei GuoThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Jiale ShaoThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Jiayan LiThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China.
Yukun DuThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China. qdfydyk0728@163.com.
Jun DongDepartment of Spinal Surgery, Shandong Provincial Hospital, Shandong First Medical University, Jinan, 250021, Shandong, China. tungjun@163.com.
Yongming XiThe affiliated hospital of Qingdao University, No. 59 Haier Road, Laoshan District, Qingdao, 266100, Shandong Province, China. xym700118@163.com.

Funding

Medicine Plus Joint Research Program of Qingdao University YX2024303Qingdao Technology-Benefiting-People Program, grant numbers No. 23-2-8-smjk-9-nshTaishan Scholars Program of Shandong Province No.tstp 20250511
6 · The paper itself

Abstract

purposeTo establish a risk prediction model for postoperative outcomes in patients with ossification of the posterior longitudinal ligament (OPLL), identify key risk factors, and provide a theoretical basis for personalized treatment.

methodsClinical data of 384 OPLL patients undergoing cervical spine surgery were retrospectively analyzed. Potential predictors were screened using univariate analysis, and independent risk factors were determined through multivariate logistic regression. A dynamic nomogram was constructed, and its performance was evaluated with the concordance index (C-index), receiver operating characteristic (ROC) curve, Hosmer-Lemeshow test, and decision curve analysis (DCA).

resultsFour independent risk factors were identified and incorporated into the prediction model. The model demonstrated high accuracy and stability, with C-index values of 0.880 (training cohort) and 0.915 (validation cohort). ROC curve analysis confirmed excellent discrimination, while calibration and DCA showed good clinical applicability.

conclusionAdvanced age, history of trauma, surgical approach, and spinal cord T2 hyperintensity on imaging are independent predictors of postoperative outcomes in OPLL patients. The developed nomogram provides a reliable tool for individualized risk assessment and clinical decision-making. These findings warrant further validation in multicenter cohorts.

Indexed as

Cervical VertebraeOssification of Posterior Longitudinal LigamentPostoperative ComplicationsAdultAgedFemaleHumansMaleMiddle AgedNomogramsRetrospective StudiesRisk AssessmentRisk FactorsTreatment Outcome

Identifiers

PMID41013529
PMCPMC12465759

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.