Evidence map›Paper›PMID 41013430›Full record

SynthesisBMC infectious diseases2025

Survival of kidney transplantation in people living with HIV/AIDS: a systematic review and meta-analysis.

Ka Chun Leung, Wincy Wing Sze Ng, Jonathan Ciofani, Wendy Kwok

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ka Chun LeungDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong Special Administrative Region, China. kc.leung4@ha.org.hk.
Wincy Wing Sze NgAdult Intensive Care Unit, Queen Mary Hospital, Hong Kong Special Administrative Region, China.
Jonathan CiofaniSydney Medical School, The University of Sydney, Sydney, Australia.
Wendy KwokSchool of Public Health, Faculty of Medicine, Imperial College, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe 2013 HIV Organ Policy Equity (HOPE) Act expanded kidney transplantation eligibility for people with HIV/AIDS (PWH), marking a significant milestone and necessitating updated reviews on the outcomes of renal transplantations on PWH.

objectiveTo assess kidney transplantation outcomes in PWH, including patient and graft survival, graft rejection, and infection rates.

methodWe conducted a systematic review of studies published between 1990 and 2023. Included studies reported on kidney transplantation outcomes in PWH, focusing on graft and patient survival, rejection, and infections and compared with HIV-negative kidney graft recipients.

resultOut of 743 studies, 49 prospective and retrospective studies were included, with data of 6174 PWHs analysed. At one year post-transplant, patient survival in PWH was high at 94% (95% CI: 92.83–94.97%), with a decrease to 83% beyond five years (95% CI: 76.50–87.64%). Graft survival exhibited similar trends. Graft rejection rates increased from 26% in one year to 39% over five years. There were no significant differences in short- to medium-term recipient survival rates between PWH and HIV-negative individuals.

conclusionKidney transplantation is a viable option for PWH, with short- to medium-term outcomes comparable to HIV-negative recipients. Future research should focus on optimizing long-term outcomes.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsKidney TransplantationFemaleGraft RejectionGraft SurvivalHumansAntiretroviral TherapyHIV/AIDSHuman Immunodeficiency VirusKidney TransplantationPeople with HIV

Identifiers

PMID41013430
PMCPMC12465869

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.