Evidence map›Paper›PMID 41013405›Full record

ArticleNutrition journal2025

Association between carbohydrate intake and the risk of psoriasis: a prospective cohort study based on UK Biobank.

Hao Lin, Yudan Yang, Chunlei He, Manli Wang, Ding Ye, Xiaohui Sun, Jing Guo, Jiayu Li, Yingying Mao

Abstract read
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In one paragraph

Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Hao LinDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yudan YangDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Chunlei HeDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Manli WangDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Ding YeDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xiaohui SunDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Jing GuoDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Jiayu LiDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China. ljy@zcmu.edu.cn.
Yingying MaoDepartment of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China. myy@zcmu.edu.cn.

Funding

National Natural Science Foundation of China 82174208Science Fund for Distinguished Young Scholars of Zhejiang Province LY22H260005
6 · The paper itself

Abstract

backgroundResearch on the association between carbohydrate intake and psoriasis risk is limited. We aimed to examine the associations of carbohydrate and its different subtypes with psoriasis risk, as well as the interaction between genetic predisposition and carbohydrate intake.

methodsWe performed a prospective cohort study based on UK Biobank that included 210,474 participants who did not have psoriasis at baseline. A 24-hour dietary assessment tool was used to assess detailed dietary intake information. Incident psoriasis events were identified through hospitalization records. The association between carbohydrate intake and psoriasis was examined by Cox proportional hazard regression models. Multiplicative interaction between genetic risk and carbohydrate intake was assessed by incorporating a cross-product term in the model.

resultsA total of 1907 incident psoriasis events were recorded during the follow-up period (median: 13.25 years). Compared to the lowest intake quartile (Q1), the highest intake quartile (Q4) of total sugars [HR (95% CI) = 1.14 (1.01-1.29), FDR-P

conclusionIntake of total sugars, free sugar, and sucrose was positively associated with psoriasis risk, while fiber and starch were inversely associated.

Indexed as

DietDietary CarbohydratesPsoriasisAdultAgedBiological Specimen BanksFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsUK BiobankUnited KingdomDietary CarbohydratesAssociationCarbohydrate intakeCohort studyGenetic riskPsoriasis

Identifiers

PMID41013405
PMCPMC12465716

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