Evidence map›Paper›PMID 41013344›Full record

ArticleBMC infectious diseases2025

Medical complexity and healthcare utilization among patients attending three U.S. post-COVID clinics.

Miriam A M Nji, Elizabeth M Briones, Anindita Issa, Maureen Tierney, Jeanne Bertolli, Surendra Barshikar, Elizabeth R Unger, Juan Wisnivesky, Quan Vu, David Quimby and 5 more

Abstract readMulticenter Study
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Miriam A M NjiNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Elizabeth M BrionesNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Anindita IssaNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA. lxo4@cdc.gov.
Maureen TierneyCreighton University School of Medicine, CHI Health, Omaha, NE, USA.
Jeanne BertolliNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Surendra BarshikarUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Elizabeth R UngerNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Juan WisniveskyDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
Quan VuNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA.
David QuimbyCreighton University School of Medicine, CHI Health, Omaha, NE, USA.
Joseph AbramsNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Nikhil JaganCreighton University School of Medicine, CHI Health, Omaha, NE, USA.
Sasha ManouchehripourUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Martin LaguerreUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Jennifer R CopeNational Center for Emerging and Zoonotic Infections, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients who do not fully recover or develop new symptoms following SARS-CoV-2 infection require follow-up and sometimes seek care at specialized multidisciplinary care clinics. We aimed to describe the clinical characteristics and care needs of patients at three such post-COVID clinics.

methodsWe conducted a multisite retrospective electronic chart review of 984 patients, aged ≥ 18 years, who visited one of three post-COVID clinics at least 28 days after a clinical or polymerase chain reaction (PCR)-confirmed diagnosis of SARS-CoV-2 infection between January 20, 2020, and March 31, 2021. The clinics were located in Omaha, Nebraska, New York City, New York, and Dallas, Texas. Patient records were obtained through September 30, 2021. Data on clinical evaluations and healthcare provider visits were abstracted by trained clinical personnel using a standardized health record abstraction tool.

resultsThe median age was 52 years (range 18-89 years), 59.9% were female, and 69.0% were White. Of 984 patients, 79.9% had SARS-CoV-2 infection that was confirmed by PCR, 32.1% had three or more comorbid conditions, and 39.4% had been hospitalized. During post-COVID follow-up, the most common symptoms were shortness of breath (59.2%), post-exertional malaise (45.6%), fatigue (43.2%), and brain fog (42.8%). Nearly one in three patients had a diagnosis of post-viral fatigue syndrome (30.1%), and pulmonary system conditions (24.4%) were also common. Overall, the 984 participants attended 3914 visits (median 3; range 1-46) over a median follow-up period of 107 days (range 1-560) between first and last post-COVID follow-up visits. Of the 984 patients, 64.3% were referred for subspecialty care notably pulmonology, cardiology, and neurology. More than a third of patients were referred for rehabilitation therapy (37.9%) including physical, occupational, speech, and psychotherapy.

conclusionAdult patients at post-COVID clinics have a wide range of symptoms and conditions that highlight the medical complexity of these patients and their need for high levels of care, including multiple health care visits and referrals for therapy. This underscores the need for well-coordinated, multidisciplinary care, and planning of health resources for post-COVID-19 follow-up care.

Indexed as

COVID-19Patient Acceptance of Health CareAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSARS-CoV-2TexasUnited StatesYoung AdultCOVID-19 sequelaeLong COVIDPost-acute sequelae of SARS-CoV-2post-COVID clinicspost-COVID conditionsSARS-CoV-2

Identifiers

PMID41013344
PMCPMC12465321

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.