ArticleBMC gastroenterology2025
Impact of withdrawal time on the adenoma detection rate in elderly patients during unsedated colonoscopy: a retrospective multicenter study.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association Between Colonoscopy Withdrawal Time and Adenoma Detection: Evidence of a Continuous Dose-Response Relationship.Diagnostics (Basel, Switzerland) · 2026Article
- Human-machine collaboration in colorectal cancer screening: a narrative review of artificial intelligence-assisted colonoscopy.Frontiers in medicine · 2026Review
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Authors and funding
9 authors.
Funding
Abstract
backgroundColonoscopy withdrawal time is recognized as a key factor influencing the adenoma detection rate (ADR). Current clinical guidelines recommend a minimum colonoscopy withdrawal time of 6 min. However, the optimal withdrawal time for unsedated colonoscopy in elderly patients and its impact on ADR remain uncertain.
methodsIn this retrospective multicenter study, we collected the withdrawal time (excluding bowel cleansing and polyp resection time) of unsedated colonoscopy in elderly patients, to analyze the relationship between withdrawal time in 1-minute increments and ADR, and the effect of withdrawal time > 8 min compared with withdrawal time ≤ 8 min on ADR. Multivariate linear regression analysis was employed to assess the optimal withdrawal time influencing ADR.
resultsA total of 1119 samples (mean age, 70.32 ± 7.17 years; 57.28% male) were included in the analysis, with a median withdrawal time of 9 min (interquartile range [IQR], 7-13). The ADR was highest at a withdrawal time of 8 min (67.02%), while the adenocarcinoma detection rate (ACDR) peaked at a withdrawal time of 8 min (17.02%). In addition, patients with withdrawal time > 8 min exhibited a higher ADR than those with ≤ 8 min (odds ratio (OR), 1.63; 95% confidence interval (CI), 1.28-2.06; P < 0.001).
conclusionsThis retrospective multicenter study demonstrates that in elderly patients with contraindications to sedation, achieving a minimum withdrawal time of 8 min during unsedated colonoscopy is critical for optimizing ADR.
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