SynthesisBMC cardiovascular disorders2025
Association between helicobacter pylori infection and abdominal aortic aneurysm: a systematic review and meta-analysis.
Synthesis in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveAbdominal aortic aneurysm (AAA) poses a significant health risk, particularly in aging populations. This study aims to quantify the association between Helicobacter pylori (H. pylori) infection and AAA development through a systematic review and meta-analysis, emphasizing numerical results for clarity.
methodFollowing PRISMA guidelines, PubMed, SCOPUS, Medline and Embase searches were conducted. Data extraction and quality assessment were performed using standardized tools. Statistical analysis involved calculating a pooled risk ratio (RR) with a 95% confidence interval (CI) to determine the association between H. pylori infection and AAA development.
resultAmong the 8 selected studies, H. pylori infection exhibited a statistically significant overall RR of 1.54 (95% CI: 1.14-2.08, P = 0.005) for AAA development. Subgroup and sensitivity analyses were conducted to address high heterogeneity, revealing consistent results. The event rate analysis across studies showed an overall rate of 41%, (95% CI: 0.293 to 0.547) with significant variability observed among individual study populations.
conclusionThe meta-analysis confirms a significant association between H. pylori infection and AAA development, with an elevated risk ratio of 1.54. These findings underscore the importance of further research to elucidate underlying mechanisms and inform preventive strategies and interventions aimed at mitigating the risk of AAA in individuals with H. pylori infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.