Observational studyBMC cardiovascular disorders2025
Malnutrition increases the risk of atrial fibrillation.
Observational study in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005131 (Atherosclerosis Risk in Communities), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Atherosclerosis Risk in Communities (ARIC)
Who cites it
4 citing papers in PubMed.
- A nomogram as a screening tool for mild cognitive impairment in middle-aged and elderly patients with atrial fibrillation.Scientific reports · 2026Article
- Association of Prognostic Nutritional Index and New-Onset Atrial Fibrillation in Patients Undergoing Surgical Aortic Valve Replacement: A Silent Predictor in Perioperative Outcomes?Journal of clinical medicine · 2026Article
- Impact of coexisting obesity and malnutrition on the clinical outcomes of acute ischemic stroke patients treated with intravenous thrombolysis: a cohort-based study.Frontiers in nutrition · 2026Article
- Anticoagulation in Frail Older Adults with Non-Valvular Atrial Fibrillation: Clinical Challenges and Personalized Approach.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundMalnutrition and atrial fibrillation (AF) are both important challenges in current health care. Malnutrition is associated with poor prognosis of various diseases such as AF, but the effect of malnutrition on the risk of AF is not yet clear.
objectiveThe purpose of this study was to investigate the relationship between malnutrition and the risk of AF.
methodsIn this study, 13,702 cardiovascular inpatients in RED-CARPET and 10,505 community residents in ARIC were scored using the Controlled Nutritional Status (CONUT) score. We assessed the effect of malnutrition on the risk of AF. We used multivariate logistic regression to assess the association between malnutrition and AF in the RED-CARPET study, and used multivariate cox proportional hazard regression to verify the results in the ARIC study.
resultsIn RED-CARPET, according to the CONUT score, 51.2% of the participants had malnutrition, including 43.8% of mild malnutrition, 7.0% of moderate malnutrition, and 0.4% of severe malnutrition. Compared with good nutritional status, malnutrition was associated with the prevalence of AF [the adjusted odds ratio (95%CI) of mild, moderate and severe malnutrition was 1.32 (1.12,1.55), 1.85 (1.45,2.36), 2.99 (1.50,5.99), respectively]. In ARIC, malnutrition was associated with the risk of incident AF, and the risk of AF increased with the aggravation of malnutrition [ the adjusted hazard ratio(95%CI) of mild and moderate malnutrition to AF were 1.33 (1.18, 1.51) and 2.04 (1.15, 3.62), respectively].
conclusionsMalnutrition is associated with AF in both hospitalized and community populations, and the risk of AF increases with the degree of malnutrition in ARIC.
trial registrationThe RED-CARPET study was registered in the Chinese Clinical Trials Registry with the registration number ChiCTR2000039901. The ARIC study was registered in the clinicaltrials with the registration number NCT00005131. And it was obtained in https://beta.clinicaltrials.gov/study/NCT00005131?titles=ARIC&rank=2
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