Evidence map›Paper›PMID 41012929›Full record

ArticleSensors (Basel, Switzerland)2025

Transparent EEG Analysis: Leveraging Autoencoders, Bi-LSTMs, and SHAP for Improved Neurodegenerative Diseases Detection.

Badr Mouazen, Ahmed Bendaouia, Omaima Bellakhdar, Khaoula Laghdaf, Aya Ennair, El Hassan Abdelwahed, Giovanni De Marco

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Analysis of the generalization ability of graph neural networks in cross-subject EEG emotion recognition.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Badr MouazenLINP2 Lab, Paris Nanterre University, UPL Paris, 92000 Nanterre, France.ORCID 0009-0009-7110-0264
Ahmed BendaouiaInstitute for Advanced Manufacturing (IAM), University of Texas Rio Grande Valley, Edinburg, TX 78539, USA.ORCID 0000-0003-0017-9285
Omaima BellakhdarLISI Lab, Computer Science Department, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech 40000, Morocco.
Khaoula LaghdafLISI Lab, Computer Science Department, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech 40000, Morocco.
Aya EnnairLISI Lab, Computer Science Department, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech 40000, Morocco.
El Hassan AbdelwahedLISI Lab, Computer Science Department, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech 40000, Morocco.
Giovanni De MarcoLINP2 Lab, Paris Nanterre University, UPL Paris, 92000 Nanterre, France.ORCID 0000-0003-1469-1044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores the use of deep learning techniques for classifying EEG signals in the context of Alzheimer's disease (AD) and frontotemporal dementia (FTD). We propose a novel classification pipeline that combines autoencoders for feature extraction and bidirectional long short-term memory (Bi-LSTM) networks for analyzing patterns over time in EEG data. Given the complexity and high dimensionality of EEG signals, we employed an autoencoder to reduce data dimensionality while preserving key diagnostic features. The Bi-LSTM model effectively identified subtle temporal patterns in brain activity that are indicative of AD and FTD. To enhance interpretability, we applied SHapley Additive exPlanations (SHAP), providing insights into how individual features contribute to the model's predictions. We evaluated our approach on a publicly available EEG dataset from OpenNeuro, which includes resting-state EEG recordings from 88 elderly participants-36 with AD, 23 with FTD, and 29 cognitively normal controls. EEG provides a non-invasive, cost-effective tool for brain monitoring, but presents challenges such as noise sensitivity and inter-subject variability. Despite these challenges, our approach achieved 98% accuracy while maintaining transparency, making it a promising tool for clinical applications in the diagnosis of neurodegenerative diseases.

Indexed as

Alzheimer DiseaseElectroencephalographyFrontotemporal DementiaNeurodegenerative DiseasesAgedAlgorithmsAutoencoderBrainDeep LearningFemaleHumansMaleMiddle AgedSignal Processing, Computer-AssistedAlzheimer’s diseaseautoencoderbidirectional LSTMdeep learningEEG analysisexplainable AIfrontotemporal dementiamachine learningneurodegenerative diseasesSHAPsignal processingtemporal analysis

Identifiers

PMID41012929
PMCPMC12473364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.