Pharmacokinetics of Carprofen Administered Intravenously at Different Doses in Goats.

Orhan Corum, Halis Oguz, Mustafa Hitit, Duygu Durna Corum, Devran Coskun, Teslime Erdogan, Emre Bahcivan, Kamil Uney

Abstract read

In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Orhan CorumDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay 31060, Türkiye.ORCID 0000-0003-3168-2510

Halis OguzDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya 42003, Türkiye.ORCID 0000-0002-9236-0630

Mustafa HititCollege of Agriculture, Food and Natural Resources, Prairie View University, Prairie View, TX 77446, USA.

Duygu Durna CorumDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay 31060, Türkiye.ORCID 0000-0003-1567-991X

Devran CoskunDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Siirt, Siirt 56100, Türkiye.

Teslime ErdoganMinistry of National Education, Directorate of Lifelong Learning, Yenimahalle, Ankara 06560, Türkiye.

Emre BahcivanDepartment of Medical Pharmacology, Faculty of Medicine, Amasya University, Amasya 05100, Türkiye.ORCID 0000-0002-4415-1738

Kamil UneyDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya 42003, Türkiye.ORCID 0000-0002-8674-4873

Funding

The Coordination of Scientific Research Projects, University of Selcuk, Türkiye 21401137

6 · The paper itself

Abstract

This investigation focuses on understanding the pharmacokinetic behavior of intravenously administered carprofen at doses of 0.7, 1.4, and 4 mg/kg in goats. Eighteen animals were randomly assigned into three groups, with six goats per group, and blood samples were collected at 22 time points post-administration. Plasma concentrations were analyzed using a validated HPLC-UV method, and key pharmacokinetic parameters were derived using non-compartmental analysis. Results show that, at 0.7 mg/kg, carprofen exhibited the total clearance (Cl

Indexed as

carprofendifferent dosesgoatpharmacokinetics

Identifiers

PMID41012777

DOI10.3390/vetsci12090852

PMCPMC12474378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.