Evidence map›Paper›PMID 41012610›Full record

ArticleViruses2025

Predictive Factors for HBsAg Seroconversion Following Acute Hepatitis B Virus Infection: A Multicenter BUHASDER Study.

Ozge Caydasi, Derya Öztürk Engin, Ömer Karaşahin, Ayşe Batırel, Süleyman Dolu, Müge Toygar Deniz, Sıla Akhan, Kemalettin Özden, Selma Tosun, Burak Sarıkaya and 18 more

Abstract readMulticenter Study
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Ozge CaydasiDepartment of Infectious Diseases and Clinical Microbiology, Sancaktepe Education and Research Hospital, Health Sciences University, 34785 Istanbul, Turkey.ORCID 0000-0003-2804-3101
Derya Öztürk EnginDepartment of Infectious Diseases and Clinical Microbiology, Sancaktepe Education and Research Hospital, Health Sciences University, 34785 Istanbul, Turkey.
Ömer KaraşahinDepartment of Infectious Diseases and Clinical Microbiology, Erzurum Education and Research Hospital, Health Sciences University, 25070 Erzurum, Turkey.ORCID 0000-0002-4245-1534
Ayşe BatırelDepartment of Infectious Diseases and Clinical Microbiology, Kartal Dr. Lütfi Kırdar City Hospital, Health Sciences University, 34865 Istanbul, Turkey.
Süleyman DoluDepartment of Gastroenterology, Faculty of Medicine, Dokuz Eylül University, 35340 Izmir, Turkey.
Müge Toygar DenizDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Kocaeli University, 41380 Kocaeli, Turkey.ORCID 0000-0002-6946-2727
Sıla AkhanDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Kocaeli University, 41380 Kocaeli, Turkey.
Kemalettin ÖzdenDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Atatürk University, 25240 Erzurum, Turkey.
Selma TosunDepartment of Infectious Diseases and Clinical Microbiology, Izmir City Hospital, Health Sciences University, 35170 Izmir, Turkey.ORCID 0000-0001-9844-9399
Burak SarıkayaDepartment of Infectious Diseases and Clinical Microbiology, Sultan 2. Abdulhamid Han Education and Research Hospital, Health Sciences University, 34668 Istanbul, Turkey.ORCID 0000-0002-0026-1927
Levent GörenekDepartment of Infectious Diseases and Clinical Microbiology, Sultan 2. Abdulhamid Han Education and Research Hospital, Health Sciences University, 34668 Istanbul, Turkey.
Merve Çelik AydoğduDepartment of Infectious Diseases and Clinical Microbiology, Sancaktepe Education and Research Hospital, Health Sciences University, 34785 Istanbul, Turkey.
Eyüp ArslanDepartment of Infectious Diseases and Clinical Microbiology, Sancaktepe Education and Research Hospital, Health Sciences University, 34785 Istanbul, Turkey.ORCID 0000-0002-5490-465X
Fatma Yılmaz KaradağDepartment of Infectious Diseases and Clinical Microbiology, Sancaktepe Education and Research Hospital, Health Sciences University, 34785 Istanbul, Turkey.ORCID 0000-0003-4657-5291
Serpil ErolDepartment of Infectious Diseases and Clinical Microbiology, Haydarpaşa Numune Education and Research Hospital, Health Sciences University, 34668 Istanbul, Turkey.
Semiha Çelik EkinciDepartment of Infectious Diseases and Clinical Microbiology, Fatih Sultan Mehmet Education and Research Hospital, Health Sciences University, 34752 Istanbul, Turkey.
Ahmet ŞahinDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Dr Ersin Arslan Education and Research Hospital, Gaziantep Islam Science and Technology University, 27010 Gaziantep, Turkey.
Müge ÖzgülerDepartment of Infectious Diseases and Clinical Microbiology, Elazığ Fethi Sekin City Hospital, Health Sciences University, 23280 Elazig, Turkey.
Pınar Yürük AtasoyDepartment of Infectious Diseases and Clinical Microbiology, Ankara Bilkent City Hospital, Health Sciences University, 06800 Ankara, Turkey.
Derya SeymanDepartment of Infectious Diseases and Clinical Microbiology, Antalya Education and Research Hospital, Health Sciences University, 07100 Antalya, Turkey.
Süleyman YıldırımDepartment of Gastroenterology, Izmir City Hospital, Health Sciences University, 35170 Izmir, Turkey.
Gözde Derviş HakimDepartment of Gastroenterology, Izmir City Hospital, Health Sciences University, 35170 Izmir, Turkey.
Tuba Damar ÇakırcaDepartment of Infectious Diseases and Clinical Microbiology, Health Sciences University, Şanlıurfa Education and Research Hospital, 63300 Sanliurfa, Turkey.
Özlem Bayraktar SaralDepartment of Infectious Diseases and Clinical Microbiology, Trabzon Kanuni Education and Research Hospital, Health Sciences University, 61040 Trabzon, Turkey.
Tuğba SarıDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Pamukkale University, 20070 Denizli, Turkey.ORCID 0000-0003-3204-2371
Türkkan Öztürk KaygusuzDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Fırat University, 23119 Elazig, Turkey.
Süleyman GünayDepartment of Gastroenterology, Faculty of Medicine, İzmir Katip Çelebi University, 35620 Izmir, Turkey.ORCID 0000-0002-1159-1577
Şükran KöseDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Dokuz Eylül University, 35340 Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experience with the effect of antiviral therapy on HBsAg seroconversion in acute hepatitis B is limited. We aimed to evaluate the factors affecting HBsAg seroconversion in patients with acute hepatitis B (AHB) receiving antiviral treatment. We performed a retrospective and multicenter study involving 107 adult patients who received antiviral treatment for AHB between January 2018 and December 2023. The median age was 48 (min-max, 18-91) years, and 66.3% of the patients were male; 70 patients with 24-week follow-up (15 patients without HBsAg seroconversion versus 55 patients with HBsAg seroconversion) were compared based on HBsAg seroconversion status. Multivariate logistic regression analysis revealed that age was independently associated with HBsAg seroconversion (odds ratio = 0.926; 95% confidence interval (CI) 0.874 to 0.981;

Indexed as

Hepatitis BHepatitis B Surface AntigensHepatitis B virusSeroconversionAcute DiseaseAdolescentAdultAgedAged, 80 and overAge FactorsAntiviral AgentsFemaleHumansMaleMiddle AgedRetrospective StudiesAntiviral AgentsHepatitis B Surface Antigensacute hepatitis BentecavirHBsAg seroconversionpredictortenofovir

Identifiers

PMID41012610
PMCPMC12474156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.