Evidence map›Paper›PMID 41012529›Full record

ArticlePharmaceutics2025

Improved Dual-Modality Bioequivalence Evaluation of Topical Formulations Within Human Skin Using Stimulated Raman Scattering Microscopy.

Dandan Tu, Nick-Sidney Lemberger, Kristin Wallmeier, Jackson Riseman, Benjamin A Kuzma, Yuxiao Wei, Ting Chean Khoo, Elena Rantou, Priyanka Ghosh, Markham C Luke and 3 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Dandan TuWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, CNY149-3, 13th St, Charlestown, MA 02129, USA.ORCID 0000-0003-3827-6486
Nick-Sidney LembergerInstitute of Applied Physics, University of Münster, 48149 Münster, Germany.ORCID 0009-0004-7959-0513
Kristin WallmeierInstitute of Applied Physics, University of Münster, 48149 Münster, Germany.ORCID 0009-0006-2822-0488
Jackson RisemanWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, CNY149-3, 13th St, Charlestown, MA 02129, USA.ORCID 0000-0001-8088-5483
Benjamin A KuzmaWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, CNY149-3, 13th St, Charlestown, MA 02129, USA.ORCID 0000-0002-9900-8912
Yuxiao WeiWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, CNY149-3, 13th St, Charlestown, MA 02129, USA.ORCID 0000-0002-5392-160X
Ting Chean KhooWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, CNY149-3, 13th St, Charlestown, MA 02129, USA.ORCID 0000-0002-0451-4653
Elena RantouOffice of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.ORCID 0009-0002-7291-5771
Priyanka GhoshOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.ORCID 0000-0003-1702-3818
Markham C LukeOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.ORCID 0000-0001-6887-3156
Sam G RaneyOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.ORCID 0000-0003-3562-8175
Carsten FallnichInstitute of Applied Physics, University of Münster, 48149 Münster, Germany.ORCID 0000-0002-2837-0615
Conor L EvansWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, CNY149-3, 13th St, Charlestown, MA 02129, USA.ORCID 0000-0003-2185-6505

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
FDA HHS U01 FD006698Food and Drug Administration (FDA) of the U.S. Department of Health and Human Services (HHS) 1U01FD006698-01NIGMS NIH HHS T32 GM007753NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bioequivalencecutaneous pharmacokineticslight intensity normalizationmulti-modalitystimulated Raman microscopetopical product

Identifiers

PMID41012529
PMCPMC12473907

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.