Evidence map›Paper›PMID 41012498›Full record

ArticlePharmaceutics2025

Comparison of the Effect of the Combination of Sodium Valproate and Sodium Dichloroacetate on the Expression of

Dovydas Gečys, Laimis Akramas, Aidanas Preikšaitis, Ingrida Balnytė, Arūnas Vaitkevičius, Julija Šimienė, Donatas Stakišaitis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dovydas GečysLaboratory of Molecular Cardiology, Institute of Cardiology, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Laimis AkramasDca Farma, UAB, 47296 Kaunas, Lithuania.
Aidanas PreikšaitisClinic of Neurology and Neurosurgery, Center of Neurosurgery, Faculty of Medicine, Vilnius University, 03101 Vilnius, Lithuania.
Ingrida BalnytėDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.
Arūnas VaitkevičiusClinic of Neurology and Neurosurgery, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University Hospital Santaros Klinikos, Vilnius University, 08661 Vilnius, Lithuania.
Julija ŠimienėLaboratory of Molecular Oncology, National Cancer Institute, 08660 Vilnius, Lithuania.ORCID 0000-0001-9358-8859
Donatas StakišaitisDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.

Funding

The European Union funds allocated for 2021-2027 under the activity "Promote innovation supply" of the progress measure No. 05-001-05-07 by Order No. 4-398 of the Minister of Economy and Innovation of the Republic of Lithuania No. 02-014-K-0036.
6 · The paper itself

Abstract

The search for an effective treatment for adult high-grade glioblastoma (GBM) remains urgent.

Indexed as

CDH1CDH2EZH2GFAPglioblastomaIDH-wild-typeKCC2NKCC1primary cellssodium dichloroacetatesodium valproatetemozolomide

Identifiers

PMID41012498
PMCPMC12473538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.