Evidence map›Paper›PMID 41012384›Full record

ArticleToxics2025

Effects of Gossypol Exposure on Ovarian Reserve Function: Comprehensive Risk Assessment Based on TRAEC Strategy.

Xiaoyan Sun, Jia Ying, Xuan Ma, Yunong Zhong, Ran Huo, Qingxia Meng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoyan SunCenter of Reproduction and Genetics, State Key Laboratory of Reproductive Medicine and Offspring Health, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215000, China.ORCID 0000-0001-5898-7010
Jia YingState Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing 210000, China.
Xuan MaThe Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi Medical Center, Nanjing Medical University, Wuxi 214000, China.
Yunong ZhongState Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing 210000, China.ORCID 0009-0002-7260-8042
Ran HuoState Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing 210000, China.
Qingxia MengCenter of Reproduction and Genetics, State Key Laboratory of Reproductive Medicine and Offspring Health, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215000, China.ORCID 0009-0005-0666-7425

Funding

Suzhou Municipal Health Commission GSWS2023106
6 · The paper itself

Abstract

This study evaluated the reproductive toxicity and reversibility of gossypol exposure in female Institute of Cancer Research (ICR) mice using the Targeted Risk Assessment of Environmental Chemicals (TRAEC) framework. Mice treated with gossypol (20 mg/kg/day, 30 days) showed reduced body weight (35.90 ± 3.19 g vs. 30.26 ± 0.91 g,

Indexed as

gossypolovarian reservereproductive toxicityTRAEC strategy

Identifiers

PMID41012384
PMCPMC12473940

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.