Evidence map›Paper›PMID 41012368›Full record

ReviewToxics2025

Polycyclic Aromatic Hydrocarbons in Marine Environments Affect Fish Reproduction-A Critical Review.

Roberta Pozzan, Aliciane de Almeida Roque, Hissashi Iwamoto, Fernando de Campos Guerreiro, Ana Paula da Silva, Dámaso Angel Rubio-Vargas, Micheli de Marchi, Felipe de Oliveira, Walter José Martínez-Burgos, Maritana Mela Prodocimo and 1 more

Abstract readReview
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roberta PozzanCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.ORCID 0000-0002-5044-9792
Aliciane de Almeida RoqueCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.ORCID 0000-0003-4358-1928
Hissashi IwamotoDepartment of Bioprocess Engineering and Biotechnology, Federal University of Paraná, Curitiba CEP 82590-300, PR, Brazil.ORCID 0000-0002-9572-0363
Fernando de Campos GuerreiroCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.ORCID 0000-0002-5865-9276
Ana Paula da SilvaCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.ORCID 0000-0001-8150-5630
Dámaso Angel Rubio-VargasCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.ORCID 0000-0002-9711-1000
Micheli de MarchiCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.
Felipe de OliveiraCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.ORCID 0009-0001-9512-7383
Walter José Martínez-BurgosDepartment of Bioprocess Engineering and Biotechnology, Federal University of Paraná, Curitiba CEP 82590-300, PR, Brazil.ORCID 0000-0003-4377-6530
Maritana Mela ProdocimoCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.
Ciro Alberto de Oliveira RibeiroCell Toxicology Laboratory, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Curitiba CEP 81531-970, PR, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biodiversity of marine and coastal ecosystems is constantly threatened by pollutants from a diversity of human activities. The polycyclic aromatic hydrocarbons (PAHs) are a class of pollutants widely released and deposited in these environments, leading to several impacts on the community of organisms that integrate these ecosystems. As lipophilic compounds, PAHs become bioavailable to organisms and can enter the trophic chain, leading to physiological changes and affecting different levels of biological organization. Several studies demonstrate that PAHs act as endocrine disruptors in marine fish, interfering with endocrine signaling through hormonal disturbances and, consequently, causing inhibition or overexpression of genes, enzymes, and proteins that are essential for reproduction success. These changes, in turn, can lead to population decline and cause immeasurable ecosystem damage. This review synthesizes studies published mainly between 2015 and 2025, aiming to critically present research that identifies different endocrine-reproductive changes in marine fish species exposed to PAHs in contaminated sites, highlighting the involved cellular mechanisms. Finally, we provide a survey of patents developed to identify PAHs in aquatic environments and how these techniques can be used in marine biomonitoring to evaluate water quality and the risk of exposure to biota and human populations.

Indexed as

endocrine disruptionfish reproductionmarine biomonitoringmarine pollutionpolycyclic aromatic hydrocarbons

Identifiers

PMID41012368
PMCPMC12473899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.