Evidence map›Paper›PMID 41012259›Full record

ArticlePolymers2025

Biodegradable Zwitterionic PLA-Based Nanoparticles: Design and Evaluation for pH-Responsive Tumor-Targeted Drug Delivery.

Evi Christodoulou, Alexandros Tsimpolis, Konstantinos Theodorakis, Styliani Axypolitou, Ioannis Tsamesidis, Eleana Kontonasaki, Eleni Pavlidou, Dimitrios N Bikiaris

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Stimuli-responsive bioengineered platforms for precision cancer therapy.Frontiers in bioengineering and biotechnology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evi ChristodoulouDepartment of Chemistry, Laboratory of Polymer Chemistry and Technology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-2730-0778
Alexandros TsimpolisDepartment of Basic Science, Medical School, University of Crete, 70013 Heraklion, Greece.ORCID 0000-0001-6346-7714
Konstantinos TheodorakisDepartment of Basic Science, Medical School, University of Crete, 70013 Heraklion, Greece.
Styliani AxypolitouDepartment of Prosthodontics, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Ioannis TsamesidisDepartment of Prosthodontics, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-1439-3920
Eleana KontonasakiDepartment of Prosthodontics, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-7840-4828
Eleni PavlidouLaboratory of Advanced Materials and Devices, Department of Physics, Faculty of Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Dimitrios N BikiarisDepartment of Chemistry, Laboratory of Polymer Chemistry and Technology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-8458-4952

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biodegradable polyesterspaclitaxelpH-responsive drug deliverypoly(ethylene adipate)polylactic acidzwitterionic polymeric nanoparticles

Identifiers

PMID41012259
PMCPMC12473292

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.