Evidence map›Paper›PMID 41012154›Full record

ArticleVaccines2025

Experimental Efficacy of a Novel Combined Vaccine of Porcine Circovirus Types 2a/d,

Jeongmin Suh, Sehyeong Ham, Hyejin Na, Youngkook You, Bumsoo Park, Chanhee Chae

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeongmin SuhDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Republic of Korea.
Sehyeong HamDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Republic of Korea.
Hyejin NaDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Republic of Korea.
Youngkook YouCARESIDE Co., Ltd., Seongnam-si 13209, Republic of Korea.
Bumsoo ParkCARESIDE Co., Ltd., Seongnam-si 13209, Republic of Korea.
Chanhee ChaeDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Republic of Korea.

Funding

Research Institute for Veterinary Science (RIVS) from the College of Veterinary Medicine and by the BK21 FOUR Future Veterinary Medicine Leading Education and Research Center 550-20210125
6 · The paper itself

Abstract

backgroundThe efficacy of a novel combined vaccine targeting porcine circovirus types 2a/d (PCV2a/d),

methodsA total of 45 pigs were randomly allocated into nine groups (five pigs per group). Vaccinated groups received a single 2 mL intramuscular dose of the combined vaccine and were subsequently challenged with PCV2a, PCV2d,

resultsVaccinated pigs exhibited enhanced growth performance and elicited systemic immune responses, including both humoral and cellular immunity, against all four pathogens. Vaccination also significantly reduced viremia, mycoplasmal loads in laryngeal and nasal swabs, and the severity of associated lesions compared with unvaccinated controls.

conclusionsThese results indicated that the combined vaccine was efficacious and conferred protection against PCV2a, PCV2d,

Indexed as

enzootic pneumoniaMycoplasma hyopneumoniaeMycoplasma hyorhinisporcine circovirus type 2aporcine circovirus type 2dporcine respiratory disease complexvaccine

Identifiers

PMID41012154
PMCPMC12474363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.