Evidence map›Paper›PMID 41012152›Full record

ArticleVaccines2025

Cross-Neutralization of Distant Coronaviruses Strongly Correlates with Spike S2-Specific Antibodies from Immunocompetent and Immunocompromised Vaccinated SARS-CoV-2-Infected Patients.

Sara V Patel, Brooke M Leeman, Patricia J Botros, Joanna Folta, Dhiman Shahid, Anya I Rocque, Andrew S Joyal, Joseph A Vecchio, Eliza Passell, Dessie Tien and 22 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

Sara V PatelBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
Brooke M LeemanBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
Patricia J BotrosBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
Joanna FoltaBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
Dhiman ShahidBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
Anya I RocqueBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
Andrew S JoyalBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.ORCID 0009-0002-7080-1623
Joseph A VecchioBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.ORCID 0009-0004-4473-5428
Eliza PassellMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Dessie TienMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Zahra ReynoldsMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Karry SuMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Tammy D VyasMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Jatin M VyasMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.ORCID 0000-0002-9985-9565
Emory AbarMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Mamadou BarryMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.ORCID 0009-0005-1458-2528
Andrew AlexandrescuMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Zachary WallaceMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Jeffrey M DaCostaBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.ORCID 0000-0002-8590-2083
Manish C ChoudharyBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Trevor J TamuraBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Gregory E EdelsteinBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID 0009-0008-3415-3167
Yijia LiBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-5300-0571
Rinki DeoBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Jeffrey A SparksBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Julie BoucauRagon Institute of MGH, MIT, and Harvard, Boston, MA 02139, USA.ORCID 0000-0001-6731-7238
Owen T GloverRagon Institute of MGH, MIT, and Harvard, Boston, MA 02139, USA.
Amy K BarczakRagon Institute of MGH, MIT, and Harvard, Boston, MA 02139, USA.ORCID 0000-0003-3806-2381
Jacob LemieuxMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Mark J SiednerMassachusetts General Hospital, Harvard Medical School, Cambridge, MA 02114, USA.
Jonathan Z LiBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Ismael Ben FofanaBiology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.

Funding

Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI NEAFSEY, DANIEL E · 2014 to 2024
$66.5M
VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYticsP30AR072577 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Daniel Hal Solomon · 2017 to 2026
$9.8M
Joint Biology Consortium Resource-based CenterP30AR070253 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Peter A Nigrovic, Jeffrey Andrew Sparks · 2016 to 2026
$9.4M
Rheumatoid Arthritis-Related Autoantibodies, Articular Inflammation, and RA-Associated Interstitial Lung DiseaseR01AR077607 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI SPARKS, JEFFREY ANDREW · 2021 to 2025
$3.7M
Characterization of Persistent COVID-19R01AI176287 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Amy K Barczak, Jonathan Li · 2023 to 2026
$3.4M
Immunologic and Clinical Sequelae after COVID-19 in Patients with Systemic Autoimmune Rheumatic DiseasesR01AR080659 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Jeffrey Andrew Sparks · 2023 to 2026
$2.9M
Boston College Fund IgniteMassachusetts Consortium on Pathogen Readiness SARS-CoV-2 Variants ProgramNIAID NIH HHS R01 AI176287NIAID NIH HHS U19 AI110818NIAMS NIH HHS P30 AR070253NIAMS NIH HHS P30 AR072577NIAMS NIH HHS R01 AR077607NIAMS NIH HHS R01 AR080659NIH HHS P30 AR070253NIH HHS R01 AI176287NIH HHS R01 AR077607NIH HHS R01 AR080659NIH HHS U19 AI110818
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19immunocompromisedneutralizing antibodiesS2-specific antibodiesSARS-CoV-2spike-S1 dominance

Identifiers

PMID41012152
PMCPMC12474146

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.