Evidence map›Paper›PMID 41012149›Full record

ArticleVaccines2025

Leveraging Electron Beam-Inactivated Multi-Strain

Ruvindu Perera, Andi Asnayanti, Khawla S Alharbi, Anh Do, Manel Ben Larbi, Amanda P Anthney, Anna L F V Assumpcao, Komala Arsi, Geetha Kumar-Phillips, Jossie M Santamaria and 5 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Pathogenic mechanisms and vaccine development forFrontiers in microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ruvindu PereraCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.
Andi AsnayantiCenter of Excellence for Poultry Science, University of Arkansas System, Division of Agriculture, Fayetteville, AR 72701, USA.ORCID 0009-0001-6793-1833
Khawla S AlharbiCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0009-0002-9137-6734
Anh DoCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0009-0005-5119-0355
Manel Ben LarbiResearch Unit of Biodiversity and Resource Development in Mountain Areas of Tunisia (UR17AGR14), Higher School of Agriculture of Mateur, University of Carthage, Mateur 7030, Tunisia.ORCID 0000-0002-4933-7961
Amanda P AnthneyCenter of Excellence for Poultry Science, University of Arkansas System, Division of Agriculture, Fayetteville, AR 72701, USA.
Anna L F V AssumpcaoCenter of Excellence for Poultry Science, University of Arkansas System, Division of Agriculture, Fayetteville, AR 72701, USA.ORCID 0000-0002-4039-9023
Komala ArsiPoultry Production and Product Safety Research Unit, ARS, USDA, Fayetteville, AR 72791, USA.
Geetha Kumar-PhillipsCenter of Excellence for Poultry Science, University of Arkansas System, Division of Agriculture, Fayetteville, AR 72701, USA.
Jossie M SantamariaCenter of Excellence for Poultry Science, University of Arkansas System, Division of Agriculture, Fayetteville, AR 72701, USA.ORCID 0009-0009-8705-5146
Gisela F ErfCenter of Excellence for Poultry Science, University of Arkansas System, Division of Agriculture, Fayetteville, AR 72701, USA.ORCID 0000-0003-2106-3484
Tanmaie KalapalaCenter of Excellence for Poultry Science, University of Arkansas System, Division of Agriculture, Fayetteville, AR 72701, USA.
Suresh D PillaiNational Center for Electron Beam Research, Texas A&M University, College Station, TX 77845, USA.
Palmy JesudhasanPoultry Production and Product Safety Research Unit, ARS, USDA, Fayetteville, AR 72791, USA.ORCID 0000-0001-9128-4544
Adnan A K AlrubayeCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0000-0002-5122-9150

Funding

US Poultry and Egg Association (Tucker, GA, USA), E. Ford Foundation AWD-103128
6 · The paper itself

Abstract

backgroundBacterial Chondronecrosis with Osteomyelitis (BCO) is a significant issue affecting the welfare and economy of the broiler industry, causing substantial revenue losses annually. This disease is frequently associated with

methodsA total 1080 birds were assigned to four vaccination groups: eBeam-inactivated, formalin-inactivated, combination of eBeam- and formalin-inactivated, and sham (vehicle). The birds were directly exposed to aerosolized, natural BCO challenge until 56 days of age.

resultsBirds vaccinated with the eBeam-inactivated

conclusionsthe eBeam-inactivated

Indexed as

broilersChondronecrosiselectron beamlamenessOsteomyelitisStaphylococcus

Identifiers

PMID41012149
PMCPMC12474430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.