Evidence map›Paper›PMID 41011761›Full record

Trial reportPathogens (Basel, Switzerland)2025

Microbiological and Clinical Short-Term Evaluation of the Efficacy of an Herbal Tincture as an Adjunctive Treatment in the Management of Stage II, Grade A Periodontitis.

Milica Petrović, Ljiljana Kesić, Bojana Miladinović, Radmila Obradović, Ana Pejčić, Marija Bojović, Katarina Šavikin, Jelena Živković, Ivana Stanković, Dušanka Kitić

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Milica PetrovićDepartment of Oral Medicine and Periodontology, Dental Clinic, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.ORCID 0000-0001-6564-5131
Ljiljana KesićDepartment of Oral Medicine and Periodontology, Dental Clinic, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.
Bojana MiladinovićDepartment of Pharmacy, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.ORCID 0000-0003-2880-6519
Radmila ObradovićDepartment of Oral Medicine and Periodontology, Dental Clinic, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.
Ana PejčićDepartment of Oral Medicine and Periodontology, Dental Clinic, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.
Marija BojovićDepartment of Oral Medicine and Periodontology, Dental Clinic, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.ORCID 0000-0003-4586-5115
Katarina ŠavikinInstitute for Medicinal Plants Research "Dr. Josif Pančić", Tadeuša Košćuška 1, 11000 Belgrade, Serbia.ORCID 0000-0002-2086-9593
Jelena ŽivkovićInstitute for Medicinal Plants Research "Dr. Josif Pančić", Tadeuša Košćuška 1, 11000 Belgrade, Serbia.ORCID 0000-0002-9684-2637
Ivana StankovićDepartment of Oral Medicine and Periodontology, Dental Clinic, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.
Dušanka KitićDepartment of Pharmacy, Faculty of Medicine, University of Niš, 18108 Niš, Serbia.ORCID 0000-0001-8551-274X

Funding

Ministry of Education, Science and Technological Development of the Republic of Serbia 451-03-136/2025-03/200003Ministry of Education, Science and Technological Development of the Republic of Serbia 451-03-137/2025-03/200113
6 · The paper itself

Abstract

The increased incidence of periodontitis, the resistance of periodontal pathogens to antibiotics, and the adverse effects of certain drugs used in general dentistry present a strong rationale for seeking safe and effective plant-based treatments for periodontitis. HPLC-DAD analysis of a commercial herbal tincture confirmed the presence of rosmarinic acid (1102.79 ± 21.56 µg/mL), luteolin-7-

Indexed as

PeriodontitisPlant ExtractsAdultFemaleHumansMaleMiddle AgedPhytotherapyPorphyromonas gingivalisProspective StudiesTreatment OutcomeTreponema denticolaPlant Extractsanaerobic bacteriaherbal remediesperiodontal diseasepolymerase chain reaction

Identifiers

PMID41011761
PMCPMC12472954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.