Evidence map›Paper›PMID 41011736›Full record

ArticlePathogens (Basel, Switzerland)2025

Characterization of a New HIV-1 Second-Generation Circulating Recombinant Form CRF173_63A6 in the Jewish Autonomous Region of Russia.

Vasiliy E Ekushov, Maksim R Halikov, Alexei V Totmenin, Mariya E Antonets, Tatyana V Tregubchak, Andrey I Murzin, Marina N Pavlova, Anastasia M Troianova, Tatyana P Adusheva, Svetlana N Beniova and 4 more

Abstract read
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In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Vasiliy E EkushovState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.ORCID 0000-0002-0465-1260
Maksim R HalikovState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.ORCID 0009-0007-1765-1909
Alexei V TotmeninState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.
Mariya E AntonetsState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.ORCID 0000-0002-3218-0371
Tatyana V TregubchakState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.
Andrey I MurzinState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.
Marina N PavlovaRegional State Budgetary Healthcare Organization "Center for the Prevention and Control of AIDS" of the Jewish Autonomous Region, 679000 Birobidzhan, Russia.
Anastasia M TroianovaRegional State Budgetary Healthcare Organization "Center for the Prevention and Control of AIDS" of the Jewish Autonomous Region, 679000 Birobidzhan, Russia.
Tatyana P AdushevaRegional State Budgetary Healthcare Organization "Center for the Prevention and Control of AIDS" of the Jewish Autonomous Region, 679000 Birobidzhan, Russia.
Svetlana N BeniovaRegional Clinical Hospital No 2, 690011 Vladivostok, Russia.ORCID 0000-0002-8099-1267
Alexandra S ErmolitskayaRegional Clinical Hospital No 2, 690011 Vladivostok, Russia.
Irina S GorelovaRegional Clinical Hospital No 2, 690011 Vladivostok, Russia.ORCID 0000-0002-4635-4678
Alexander P AgafonovState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.ORCID 0000-0003-2577-0434
Natalya M GashnikovaState Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.

Funding

State Research and Development Program State Research Center of Virology and Biotechnology "VECTOR" #5-21
6 · The paper itself

Abstract

Studies of HIV-1 molecular epidemiology describe significant differences in HIV infection spread across geographical areas. We examined 80 HIV-1 samples from the Jewish Autonomous Region of Russia in 2024. HIV-1 genome sequences for 12 samples revealed a novel HIV-1 called CRF173_63A6. HIV-1 CRF173_63A6 was found to have arisen through recombination between a specific Russian A6 subtype and the recombinant virus CRF63_02A6, which is responsible for the PWID-associated HIV outbreak in the Siberian region of Russia. Phylogenetic analysis of pol sequences previously deposited in Genbank showed that the CRF173_63A6 samples we described are grouped into a common phylogenetic cluster that includes 54 HIV-1 samples isolated in the JAR and other areas of the Russian Far East, indicating a wide distribution of this virus genovariant. This study once again proves the significant contribution of the key PWID group not only to the development of local Russian HIV epidemics, but also to the change in the characteristics of the circulating virus population.

Indexed as

HIV-1HIV InfectionsRecombination, GeneticFemaleGenome, ViralGenotypeHumansMaleMolecular EpidemiologyPhylogenyRussiagenetic variationHIV-1molecular epidemiologyrecombination

Identifiers

PMID41011736
PMCPMC12472342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.