Evidence map›Paper›PMID 41011596›Full record

ReviewMolecules (Basel, Switzerland)2025

Fernanda de França Genuíno Ramos Campos, Willian Charles da Silva Moura, Diego Romário-Silva, Rodrigo Santos Aquino de Araújo, Inês Morais, Sofia Cortes, Fátima Nogueira, Ricardo Olimpio de Moura, Igor José Dos Santos Nascimento

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fernanda de França Genuíno Ramos CamposDrug Development and Synthesis Laboratory, Department of Pharmacy, State University of Paraíba, Campina Grande 58429-500, Brazil.
Willian Charles da Silva MouraDrug Development and Synthesis Laboratory, Department of Pharmacy, State University of Paraíba, Campina Grande 58429-500, Brazil.
Diego Romário-SilvaDepartment of Dentistry, State University of Paraíba, Campina Grande 58429-500, Brazil.ORCID 0000-0001-9724-0147
Rodrigo Santos Aquino de AraújoPostgraduate Program in Natural and Bioactive Synthetic Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0002-2403-8746
Inês MoraisGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0003-3906-694X
Sofia CortesGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0001-5850-6950
Fátima NogueiraGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0003-0313-0778
Ricardo Olimpio de MouraDrug Development and Synthesis Laboratory, Department of Pharmacy, State University of Paraíba, Campina Grande 58429-500, Brazil.ORCID 0000-0002-1590-3750
Igor José Dos Santos NascimentoDrug Development and Synthesis Laboratory, Department of Pharmacy, State University of Paraíba, Campina Grande 58429-500, Brazil.ORCID 0000-0002-2664-4336

Funding

Chamada Pública MCTI/CNPq nº 16/2024 402647/2024-6CHAMADA PÚBLICA MCTI/CNPQ Nº 16/2024 404134/2024-6Fundação para a Ciência e Tecnologia 2023.03356.BD
6 · The paper itself

Abstract

Neglected tropical diseases (NTDs) constitute a group of infectious diseases that severely affect the health of impoverished populations, and the health, economies, and health systems of affected countries. Leishmaniasis and human African trypanosomiasis (HAT) are particularly notable, and malaria, despite not being neglected, is part of the "big three" (HIV, tuberculosis, and malaria) with high incidence, increasing the probability of infection by NTDs. Therefore, efforts are ongoing in the search for new drugs targeting the enzyme

Indexed as

AcyltransferasesComputer-Aided DesignDrug DesignEnzyme InhibitorsAnimalsHumansLeishmania donovaniAcyltransferasesEnzyme Inhibitorsglycylpeptide N-tetradecanoyltransferasehuman African trypanosomiasisleishmaniasismalariamyristoyl-CoANMT inhibitorsparasitic diseases

Identifiers

PMID41011596
PMCPMC12472475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.