ArticleMicroorganisms2025
Effects of Dietary Fiber Supplementation on Gut Microbiota and Bowel Function in Healthy Adults: A Randomized Controlled Trial.
Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gut Microbiota Modulation as a Therapeutic Strategy for Insomnia: A Systematic Review of Nutritional and Botanical Interventions.Biomolecules · 2026Pooled it
- Gut Microbiome Signatures Distinguish Susceptibility from Disease Development in Type 2 Diabetes.International journal of molecular sciences · 2026Article
- The gut-brain axis as a therapeutic target in alcohol use disorder: dietary fiber, intestinal barrier integrity, and neuroinflammatory mechanisms underlying depression.Frontiers in nutrition · 2026Article
- Combined inulin, glucomannan, and medium-chain triglyceride modulate metabolic and inflammatory responses in chemotherapy-treated colorectal cancer cells.Journal of advanced pharmaceutical technology & researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This randomized, double-blind, controlled trial evaluated the effects of 4-week dietary fiber supplementation on gut microbiota, bowel-related quality of life, and secondary outcomes, including sleep and skin condition. A total of 105 healthy adults received either low-fiber foods (2.2 g/day total fiber, 1.2 g/day fermentable fiber) or high-fiber foods (8.2 g/day total fiber, including 6.4 g/day fermentable fiber). Gut microbiota was analyzed by 16S rRNA sequencing. Outcomes included stool diary, JPAC-QOL (Japanese version of the Patient Assessment of Constipation Quality of Life), OSA-MA (Oguri-Shirakawa-Azumi sleep inventory MA version), skin questionnaires, and fecal organic acids. The high-fiber group showed significant improvements in JPAC-QOL and increases in SCFA-associated genera such as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.