ArticleMicroorganisms2025
Study on the Plateau Adaptive Synergistic Mechanism of Rumen Microbiome-Metabolome-Resistome in Tibetan Sheep.
Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Integrated Omics Analysis of the Effects of Nano-Antimicrobial Peptide on the Intestinal Microbiota and Metabolome of Tibetan Sheep.Animals : an open access journal from MDPI · 2026Article
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Authors and funding
13 authors.
Funding
Abstract
Tibetan sheep are an important livestock breed adapted to the extreme environment of the Qinghai-Tibet Plateau (QTP). Their energy metabolism and environmental adaptability are highly dependent on the rumen microbiome. However, systematic comparisons of the rumen microbiome, its functions, and the resistome between plateau-adapted breeds and lowland breeds remain insufficient. In this study, 6 Tibetan sheep (TS) and 6 Hu sheep (HS) were selected. All the selected sheep had a body weight of 34 kg (±0.5 kg) and an age of 1 year (±1 month) and were all managed under local traditional natural grazing (without supplementary feeding). Using metagenomics and metabolomics techniques, systematic comparative analysis was conducted on the differences in rumen microbial community structure, functions, resistome, and metabolites between the two breeds. Metagenomic analysis showed that at the phylum level, the abundance of Bacteroidetes in the rumen of TS was significantly higher than that in HS (
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