Evidence map›Paper›PMID 41011357›Full record

ArticleMicroorganisms2025

Are "Free From" Foods Risk-Free? Lactose-Free Milk Fermentation Modulates Normal Colon in a Gut Microbiota in Vitro Model.

Flavia Casciano, Lorenzo Nissen, Alessandra Bordoni, Andrea Gianotti

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Flavia CascianoDiSTAL-Department of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, P.za G. Goidanich, 60, 47521 Cesena, Italy.
Lorenzo NissenDiSTAL-Department of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, P.za G. Goidanich, 60, 47521 Cesena, Italy.ORCID 0000-0002-7875-6321
Alessandra BordoniDiSTAL-Department of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, P.za G. Goidanich, 60, 47521 Cesena, Italy.ORCID 0000-0003-4579-1662
Andrea GianottiDiSTAL-Department of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, P.za G. Goidanich, 60, 47521 Cesena, Italy.ORCID 0000-0002-8847-6251

Funding

Ministero dell'università e della ricerca ON Foods - Research and innovation network on food and nutrition Sustainability, Safety and Security - Working ON Foods" (Project code PE00000003).
6 · The paper itself

Abstract

Nowadays, the consumption of "free from" foods by non-specific consumers is increasing, partly due to a misperception of labels that make them seem healthier. These foods are formulated for consumers with allergies or diseases that limit their diet, and it is not known if there are more benefits than risks for healthy consumers. For example, there is no work investigating the interaction between lactose-free milk and the colonic microbiome of healthy individuals. To focus on the potential modulation of gut microbiota of healthy subjects by lactose-free milk, we performed an in vitro simulation of digestion and fermentation, integrating microbiomics and metabolomics approaches to study changes in gut microbiota populations and metabolite production. Results indicated that lactose-free and lactose-containing milk differently modulated colonic microbiota based on several microbiological indicators, including the reduction in

Indexed as

Bifidobacterium spp.dairyEnterobacteriaceaegut microbiotahealth halo

Identifiers

PMID41011357
PMCPMC12471900

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.