Evidence map›Paper›PMID 41011334›Full record

ArticleMicroorganisms2025

Poly(hexamethylene guanidine): An Effective Compound in Tackling Persistent Bacterial Subpopulations.

Weilin Liu, Jiang Zhang, Liang Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Weilin LiuCollege of Bioengineering, Beijing Polytechnic University, Beijing 100176, China.
Jiang ZhangCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Liang ChenCollege of Bioengineering, Beijing Polytechnic University, Beijing 100176, China.ORCID 0000-0003-4895-6506

Funding

the Project of Beijing Educational Science Planning CDDB22223the Science and Technology Program of Beijing Polytechnic University 2024X001-KXY
6 · The paper itself

Abstract

Persistent bacteria (PB) are a subpopulation of dormant cells that tolerate high antibiotic concentrations and cause chronic, hard-to-treat infections, posing a serious global health threat. In this study, the antibacterial efficacy of six cationic polymers, poly(hexamethylene guanidine) (PHMG), polyethyleneimines of different molecular weights, α-polylysine, ε-polylysine, and polyacrylamide, against persistent bacteria was systematically evaluated. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of these cationic polymers against susceptible and persistent methicillin-susceptible

Indexed as

antibacterial performanceantibiotic resistancecationic polymerspersistent bacteriapoly(hexamethylene guanidine)

Identifiers

PMID41011334
PMCPMC12471952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.