Evidence map›Paper›PMID 41011308›Full record

ArticleMicroorganisms2025

pDNA Impurities in mRNA Vaccines.

Luca Roncati, Nazha Ghaleb, Joya Ghaleb, Karl Kfoury

Abstract readEditorial
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luca RoncatiDepartment of Life Sciences, Health, and Health Care Professions, School of Medicine and Surgery, Link Campus University, 00165 Rome, Italy.ORCID 0000-0001-6949-2216
Nazha GhalebDepartment of Clinical Laboratory Sciences, Faculty of Health Sciences, Balamand University, 00100 Tripoli, Lebanon.
Joya GhalebDepartment of Medicine, Faculty of Medicine and Medical Sciences, Balamand University, 00100 Tripoli, Lebanon.
Karl KfouryDepartment of Medicine, Faculty of Medicine and Medical Sciences, Balamand University, 00100 Tripoli, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Funded during the emergency phase of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, messenger RNA (mRNA) vaccines are single-stranded, 5'-capped mRNAs produced using a cell-free in vitro transcription from the corresponding plasmid DNA (pDNA) templates, encoding the viral spike (S) protein of SARS-CoV-2 [...].

Identifiers

PMID41011308
PMCPMC12471613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.