Evidence map›Paper›PMID 41011284›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Comparative Study of Ferrocene- and Indene-Based Tamoxifen Derivatives of Different Molecular Flexibility on High-Mortality Cancer Cell Lines.

Márton Kalabay, Zsófia Szász, Eszter Lajkó, Bálint Bagu, Éva Pállinger, Cintia Duró, Tamás Jernei, Antal Csámpai, Angéla Takács, László Kőhidai

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Márton KalabayDepartment of Genetics, Cell- and Immunobiology, Faculty of Medicine, Semmelweis University, Nagyvárad Square 4, 1085 Budapest, Hungary.
Zsófia SzászDepartment of Genetics, Cell- and Immunobiology, Faculty of Medicine, Semmelweis University, Nagyvárad Square 4, 1085 Budapest, Hungary.ORCID 0009-0000-3110-0379
Eszter LajkóDepartment of Genetics, Cell- and Immunobiology, Faculty of Medicine, Semmelweis University, Nagyvárad Square 4, 1085 Budapest, Hungary.ORCID 0000-0002-4796-4646
Bálint BaguDepartment of Genetics, Cell- and Immunobiology, Faculty of Medicine, Semmelweis University, Nagyvárad Square 4, 1085 Budapest, Hungary.
Éva PállingerDepartment of Genetics, Cell- and Immunobiology, Faculty of Medicine, Semmelweis University, Nagyvárad Square 4, 1085 Budapest, Hungary.
Cintia DuróDepartment of Inorganic Chemistry, Faculty of Chemistry, Eötvös Loránd University, Egyetem Square 1-3, 1053 Budapest, Hungary.
Tamás JerneiDepartment of Inorganic Chemistry, Faculty of Chemistry, Eötvös Loránd University, Egyetem Square 1-3, 1053 Budapest, Hungary.ORCID 0000-0003-4990-4281
Antal CsámpaiDepartment of Inorganic Chemistry, Faculty of Chemistry, Eötvös Loránd University, Egyetem Square 1-3, 1053 Budapest, Hungary.ORCID 0000-0003-2107-7309
Angéla TakácsDepartment of Genetics, Cell- and Immunobiology, Faculty of Medicine, Semmelweis University, Nagyvárad Square 4, 1085 Budapest, Hungary.ORCID 0000-0002-8912-8216
László KőhidaiDepartment of Genetics, Cell- and Immunobiology, Faculty of Medicine, Semmelweis University, Nagyvárad Square 4, 1085 Budapest, Hungary.ORCID 0000-0002-9002-0296

Funding

Ministri of Innovation and Technology EFOP-3.6.3-VEKOP-16-2017-00009Ministry of Innovation and Technology ÚNKP-22-3-II-SE-77 and ÚNKP-21-2-SE-35National Research, Development and Innovation Office NVKP_16-1-2016-0036
6 · The paper itself

Abstract

Tamoxifen is a well-established selective estrogen receptor modulator (SERM) widely used in breast cancer treatment, yet its efficacy varies across tumor types. To enhance its antitumor potential, we previously synthesized and investigated novel ferrocene-linked (T5, T15) derivatives. This publication is a close continuation of this work, introducing a new indene-based (T6) derivative.

Indexed as

apoptosisbreast cancerferroceneindenepancreatic cancerROStamoxifen

Identifiers

PMID41011284
PMCPMC12472596

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.