Evidence map›Paper›PMID 41011246›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Puerarin Inhibits Proliferation, Migration and Invasion of Colon Cancer Cells and Induces Apoptosis via Suppression of the PI3K/AKT Signaling Pathway.

Lin Chen, Xuhong Li, Shijie Zhao, Mengyu Hao, Heng Wang, Zhi Zhou, Xinyu Xiong, Die Yuan, Piao Luo, Luwen Wang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Suppressive Potential of Ethanolic Extracts ofInternational journal of molecular sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lin ChenState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.
Xuhong LiState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.
Shijie ZhaoState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.
Mengyu HaoKey Laboratory of Natural Product Composition and Efficacy of Qiannan Prefecture, Qiannan Medical College for Nationalities, Duyun 558000, China.
Heng WangKey Laboratory of Natural Product Composition and Efficacy of Qiannan Prefecture, Qiannan Medical College for Nationalities, Duyun 558000, China.
Zhi ZhouKey Laboratory of Natural Product Composition and Efficacy of Qiannan Prefecture, Qiannan Medical College for Nationalities, Duyun 558000, China.
Xinyu XiongKey Laboratory of Natural Product Composition and Efficacy of Qiannan Prefecture, Qiannan Medical College for Nationalities, Duyun 558000, China.
Die YuanKey Laboratory of Natural Product Composition and Efficacy of Qiannan Prefecture, Qiannan Medical College for Nationalities, Duyun 558000, China.
Piao LuoKey Laboratory of Natural Product Composition and Efficacy of Qiannan Prefecture, Qiannan Medical College for Nationalities, Duyun 558000, China.
Luwen WangState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.
Di PanState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.
Xiangchun ShenState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.ORCID 0000-0002-4333-9106
Yue ZhangState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.
Yan ChenState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Guian New District, Guiyang 561113, China.

Funding

Additional support came from the Excellent Young Talents Plans of both Guizhou Province QKHPTRC [2021]-5632Guizhou Administration of Traditional Chinese Medicine QZYY-2024-034Guizhou Medical University (2020-101), and from key regional initiatives including the Guizhou Provincial Science and Technology Key Project QKHJC-ZK [2023] ZD-034the College Student Scientific Innovation Project of Qiannan National Medical College Qnyz2024014the Guizhou High-Level Innovation Talents Program GCC [2023] 048the Guizhou Provincial Health Commission gzwkj2024-060the Guizhou Provincial Science and Technology Basic Research Program QKHJCQNA [2025] 004the Guizhou Provincial Science and Technology Innovation Talent Team Development Project QKHRCCXTD [2025] 049the Guizhou Scientific and Technological Innovation Base [2023] 003the Key Laboratory Project of Guizhou Medical University XZDSYS [2024] 003the National Natural Science Foundation of China 82273957the Program of the Guizhou Provincial Department of Science and Technology Project ZK [2024] normal 142the Scientific Research Backbone Program of Qiannan National Medical College Qnyz202206the Young Scientific and Technological Talent Growth Project of Guizhou's higher education in-stitutions [2024] 312
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

apoptosiscolon cancerepithelial–mesenchymal transitionPI3K/AKTpuerarin

Identifiers

PMID41011246
PMCPMC12472295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.