Evidence map›Paper›PMID 41011220›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Anticonvulsant Potential of 1-Aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines: Insights from Strychnine and Nicotine Models in In Vivo and In Silico Studies.

Azizbek A Azamatov, Nilufar Z Mamadalieva, Asmaa A Mandour, Sherzod N Zhurakulov, Urkhiya K Aytmuratova, Valentina I Vinogradova, Fazliddin S Jalilov, Firuza M Tursunkhodzhaeva

Abstract read
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In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Azizbek A AzamatovInstitute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan.
Nilufar Z MamadalievaInstitute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan.ORCID 0000-0003-1756-3638
Asmaa A MandourPharmaceutical Chemistry Department, Faculty of Pharmacy, Future University in Egypt, Cairo 11835, Egypt.
Sherzod N ZhurakulovInstitute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan.ORCID 0000-0002-2857-946X
Urkhiya K AytmuratovaInstitute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan.
Valentina I VinogradovaInstitute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan.
Fazliddin S JalilovFaculty of Pharmacy and Chemistry, Alfraganus University, Yuqori Qoraqamish Str. 2a, Tashkent 100190, Uzbekistan.
Firuza M TursunkhodzhaevaInstitute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan.ORCID 0000-0002-8404-0952

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

1-aryl-1,2,3,4-tetrahydroisoquinolineADMETanticonvulsantmolecular modelingnicotineseizurestrychnine

Identifiers

PMID41011220
PMCPMC12472494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.