Evidence map›Paper›PMID 41011171›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Synthesis and Structure-Affinity Relationships of Receptor Ligands with 1,3-Dioxane Structure.

Elisabeth Quick, Dirk Schepmann, Bernhard Wünsch

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elisabeth QuickInstitut für Pharmazeutische und Medizinische Chemie, Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.
Dirk SchepmannInstitut für Pharmazeutische und Medizinische Chemie, Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.ORCID 0000-0002-4725-5428
Bernhard WünschInstitut für Pharmazeutische und Medizinische Chemie, Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.ORCID 0000-0002-9030-8417

Funding

Deutsche Forschingsgemeinschaft WU 176
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2,4-disubstituted 1,3-dioxanesbutan-4-amineshomologationifenprodil binding siteligand-lipophilicity efficiency (LLE)lipophilicitymetabolic stabilityNMDA receptor affinityopioid receptor affinityPCP binding sitereceptor affinityselectivitystructure affinity relationshipssynthesisσ1 receptor

Identifiers

PMID41011171
PMCPMC12865480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.