Evidence map›Paper›PMID 41010985›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Clinical Evidence for Microbiome-Based Strategies in Cancer Immunotherapy: A State-of-the-Art Review.

Fausto Petrelli, Antonio Ghidini, Lorenzo Dottorini, Michele Ghidini, Alberto Zaniboni, Gianluca Tomasello

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. COPD-Lung Cancer Comorbidity: Mechanistic Insights and Precision Oncology Implications.International journal of chronic obstructive pulmonary disease · 2026
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fausto PetrelliOncology Unit, ASST Bergamo Ovest, 24047 Treviglio, BG, Italy.
Antonio GhidiniOncology Unit, Casa di Cura Igea, 20129 Milano, MI, Italy.ORCID 0000-0002-6142-2018
Lorenzo DottoriniOncology Unit, ASST Bergamo Ovest, 24047 Treviglio, BG, Italy.
Michele GhidiniOncology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, MI, Italy.ORCID 0000-0001-5435-1218
Alberto ZaniboniOncology Unit, Fondazione Poliambulanza, 25124 Brescia, BS, Italy.
Gianluca TomaselloOncology Unit, ASST Crema, 26013 Crema, CR, Italy.ORCID 0009-0005-0941-8547

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome has emerged as a critical determinant of immune-checkpoint inhibitor (ICI) efficacy. A narrative review of 95 clinical studies (2015-2025) shows that patients with greater gut microbial diversity and relative enrichment of commensals such as

Indexed as

Gastrointestinal MicrobiomeImmune Checkpoint InhibitorsNeoplasmsClinical Trials as TopicDrug Resistance, NeoplasmFecal Microbiota TransplantationHumansProbioticsProgression-Free SurvivalSymbiosisImmune Checkpoint Inhibitorscancerimmunotherapymicrobiomereview

Identifiers

PMID41010985
PMCPMC12471457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.