Evidence map›Paper›PMID 41010564›Full record

ReviewJournal of clinical medicine2025

Ablative Techniques for the Management of Osseous Spine Metastases: A Narrative Review.

Zach Pennington, Jonathan M Morris, Aladine Elsamadicy, Sheng-Fu Larry Lo, Joseph H Schwab, Daniel M Sciubba

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Readmission rate following surgical treatment for spinal deformity: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zach PenningtonDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-8012-860X
Jonathan M MorrisDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Aladine ElsamadicyDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT 06510, USA.
Sheng-Fu Larry LoDepartment of Neurosurgery, Zucker School of Medicine at Hofstra, Long Island Jewish Medical Center and North Shore University Hospital, Northwell Health, Manhasset, NY 11030, USA.ORCID 0000-0001-7262-2544
Joseph H SchwabDepartment of Orthopaedics, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Daniel M SciubbaDepartment of Neurosurgery, Zucker School of Medicine at Hofstra, Long Island Jewish Medical Center and North Shore University Hospital, Northwell Health, Manhasset, NY 11030, USA.ORCID 0000-0001-7604-434X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With continued improvements in systemic cancer therapies, there has been an increase in the survivorship of patients with spinal metastases. However, many patients with spinal metastases are frail and may not be able to tolerate the morbidity of open surgery. For these patients, percutaneous ablation techniques offer a minimally invasive approach that can facilitate local tumor control and pain relief. Here we describe the currently employed modalities-radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation, and laser interstitial thermal therapy (LITT)-summarize the clinical support for their use, and overview the relative risks and benefits for each. All these technologies offer to help improve local tumor control and improve oncologic pain associated with vertebral metastases, and they have become a staple of multidisciplinary spine metastasis care at many centers. As clinical experience with these technologies continues to grow, their use will likely become more widely adopted, and so understanding of their indications, risks, and benefits will become increasingly important to the practicing spine oncologist.

Indexed as

cryoablationepidural spinal cord compressionfrailtylaser interstitial thermal therapy (LITT)microwave ablation (MWA)minimally invasive surgerypercutaneous techniqueradiofrequency ablation (RFA)spine metastases

Identifiers

PMID41010564
PMCPMC12470457

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.